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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1743298
Target Type SINGLE PROTEIN
Preferred Name Sulfotransferase 4A1
Synonyms Brain sulfotransferase-like protein | NST | Nervous system sulfotransferase | ST4A1 | SULT4A1 | SULTX3 | Sulfotransferase 4A1 | hBR-STL | hBR-STL-1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Sulfotransferase 4A1 SINGLE PROTEIN Q9BR01

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000130540
Ensembl ENSG00000130540
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0004062 (aryl sulfotransferase activity)
GO:0005515 (protein binding)
GO:0008146 (sulfotransferase activity)
GO:0016740 (transferase activity)
GO:0042802 (identical protein binding)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006790 (sulfur compound metabolic process)
GO:0008150 (biological_process)
GO:0008202 (steroid metabolic process)
GO:0050427 (3'-phosphoadenosine 5'-phosphosulfate metabolic process)
Wikipedia SULT4A1

Target Cross References - Protein

Human Protein Atlas ENSG00000130540
IntAct Q9BR01
Open Targets ENSG00000130540
PharmGKB PA412
Reactome R-HSA-156584 (Cytosolic sulfonation of small molecules.)
UniProt B2R7N3 O43728 Q9BR01

Target Cross References - Domain

InterPro IPR000863 (Sulfotransferase_dom.)
IPR027417 (P-loop_NTPase.)
Pfam PF00685 (Sulfotransfer_1)

Target Cross References - Structure

PDBe 1ZD1
CREDO 1ZD1
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