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Target Report Card

Target Name and Classification

Target ID CHEMBL1743297
Preferred Name Sulfotransferase family cytosolic 2B member 1
Synonyms Alcohol sulfotransferase | HSST2 | Hydroxysteroid sulfotransferase 2 | ST2B1 | SULT2B1 | Sulfotransferase 2B1 | Sulfotransferase family cytosolic 2B member 1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Sulfotransferase family cytosolic 2B member 1 SINGLE PROTEIN O00204

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000088002
Ensembl ENSG00000088002
GO Cellular Component GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO:0005783 (endoplasmic reticulum)
GO:0005829 (cytosol)
GO:0043231 (intracellular membrane-bounded organelle)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0004027 (alcohol sulfotransferase activity)
GO:0005515 (protein binding)
GO:0008146 (sulfotransferase activity)
GO:0016740 (transferase activity)
GO:0050294 (steroid sulfotransferase activity)
GO Biological Process GO:0000103 (sulfate assimilation)
GO:0006629 (lipid metabolic process)
GO:0008202 (steroid metabolic process)
GO:0050427 (3'-phosphoadenosine 5'-phosphosulfate metabolic process)
Wikipedia SULT2B1

Target Cross References - Protein

Human Protein Atlas ENSG00000088002
IntAct O00204
Open Targets ENSG00000088002
PharmGKB PA36249
Reactome R-HSA-156584 (Cytosolic sulfonation of small molecules.)
UniProt O00204 O00205 O75814

Target Cross References - Domain

InterPro IPR000863 (Sulfotransferase_dom.)
IPR027417 (P-loop_NTPase.)
Pfam PF00685 (Sulfotransfer_1)

Target Cross References - Structure

PDBe 1Q1Q 1Q1Z 1Q20 1Q22
CREDO 1Q1Q 1Q1Z 1Q20 1Q22