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Target Report Card

Target Name and Classification

Target ID CHEMBL1743125
Preferred Name Solute carrier family 15 member 2
Synonyms Kidney H(+)/peptide cotransporter | Oligopeptide transporter, kidney isoform | PEPT2 | Peptide transporter 2 | SLC15A2 | Solute carrier family 15 member 2
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc15 family of peptide transporters

Target Components

Component Description Relationship Accession
Solute carrier family 15 member 2 SINGLE PROTEIN Q16348

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000163406
Ensembl ENSG00000163406
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0005215 (transporter activity)
GO:0005515 (protein binding)
GO:0015198 (oligopeptide transporter activity)
GO:0015293 (symporter activity)
GO:0015333 (peptide:proton symporter activity)
GO Biological Process GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0006857 (oligopeptide transport)
GO:0015031 (protein transport)
GO:0015833 (peptide transport)
GO:0015893 (drug transport)
GO:0015992 (proton transport)
GO:0055085 (transmembrane transport)
Wikipedia SLC15A2

Target Cross References - Protein

Human Protein Atlas ENSG00000163406
IntAct Q16348
Open Targets ENSG00000163406
PharmGKB PA35812
Reactome R-HSA-427975 (Proton/oligopeptide cotransporters.)
UniProt A8K1A5 B4E2A7 Q16348

Target Cross References - Domain

InterPro IPR000109 (POT_fam.)
IPR004768 (Oligopep_transport.)
IPR018456 (PTR2_symporter_CS.)
IPR020846 (MFS_dom.)
IPR029028 (Alpha/beta_knot_MTases.)
Pfam PF00854 (PTR2)