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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1671609
Target Type SINGLE PROTEIN
Preferred Name ERO1-like protein alpha
Synonyms ERO1-L | ERO1-L-alpha | ERO1-like protein alpha | ERO1L | Endoplasmic oxidoreductin-1-like protein | Oxidoreductin-1-L-alpha
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
ERO1-like protein alpha SINGLE PROTEIN Q96HE7

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000197930
Ensembl ENSG00000197930
GO Cellular Component GO:0005788 (endoplasmic reticulum lumen)
GO:0005789 (endoplasmic reticulum membrane)
GO:0005792 (microsome)
GO Molecular Function GO:0015036 (disulfide oxidoreductase activity)
GO:0016671 (oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)
GO:0050660 (flavin adenine dinucleotide binding)
GO Biological Process GO:0006467 (protein thiol-disulfide exchange)
GO:0006810 (transport)
GO:0009266 (response to temperature stimulus)
GO:0022900 (electron transport chain)
GO:0051085 (chaperone mediated protein folding requiring cofactor)
Wikipedia ERO1L

Target Cross References - Protein

Human Protein Atlas ENSG00000197930
PharmGKB PA27862
Reactome REACT_15380 (Diabetes pathways.)
UniProt A8K9X4 A8MYW1 Q7LD45 Q96HE7 Q9P1Q9 Q9UKV6

Target Cross References - Domain

InterPro IPR007266 (ER_oxidoreductin-1.)
Pfam PF04137 (ERO1)

Target Cross References - Structure

PDBe 3AHQ 3AHR
CREDO 3AHQ 3AHR
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