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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1641347
Preferred Name Solute carrier family 22 member 6
Synonyms Object
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc22 family of organic cation and anion transporters

Target Components

Component Description Relationship Accession
Solute carrier family 22 member 6 SINGLE PROTEIN Q4U2R8

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000197901
Ensembl ENSG00000197901
GO Cellular Component GO:0005887 (integral component of plasma membrane)
GO:0070062 (extracellular exosome)
GO:0005901 (caveola)
GO:0043234 (protein complex)
GO:0016323 (basolateral plasma membrane)
GO:0005886 (plasma membrane)
GO Molecular Function GO:0008514 (organic anion transmembrane transporter activity)
GO:0031404 (chloride ion binding)
GO:0005452 (inorganic anion exchanger activity)
GO:0015347 (sodium-independent organic anion transmembrane transporter activity)
GO Biological Process GO:0015742 (alpha-ketoglutarate transport)
GO:0015711 (organic anion transport)
GO:0055085 (transmembrane transport)
GO:0098656 (anion transmembrane transport)
GO:0043252 (sodium-independent organic anion transport)
GO:0051260 (protein homooligomerization)
GO:0097254 (renal tubular secretion)
GO:0031427 (response to methotrexate)
Wikipedia Organic_anion_transporter_1

Target Cross References - Protein

Human Protein Atlas ENSG00000197901
IntAct Q4U2R8
Guide to Pharmacology 1025 (Organic anion transporter 1)
PharmGKB PA388
UniProt Q4U2R8 Q8N192 Q9NQA6 O95187 O95742 Q9UEQ8 A8MY93 Q7LDA0 B2D0R6 Q9NQC2 Q9UBG6

Target Cross References - Domain

InterPro IPR004749 (Orgcat_transp/SVOP.)
IPR020846 (MFS_dom.)
IPR005828 (MFS_sugar_transport_like.)
Pfam PF00083 (Sugar_tr)