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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1628480
Target Type SINGLE PROTEIN
Preferred Name Polycystic kidney disease 2-like 1 protein
Synonyms PKD2L | PKD2L1 | PKDL | Polycystic kidney disease 2-like 1 protein | Polycystin-2 homolog | Polycystin-2L1 | Polycystin-L | Polycystin-L1 | TRPP3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • ion channel > voltage-gated ion channel > transient receptor potential channel

Target Components

Component Description Relationship Accession
Polycystic kidney disease 2-like 1 protein SINGLE PROTEIN Q9P0L9

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000107593
Ensembl ENSG00000107593
GO Cellular Component GO:0016021 (integral to membrane)
GO Molecular Function GO:0005227 (calcium activated cation channel activity)
GO:0005509 (calcium ion binding)
GO:0008092 (cytoskeletal protein binding)
GO Biological Process GO:0007165 (signal transduction)
Wikipedia PKD2L1

Target Cross References - Protein

Human Protein Atlas ENSG00000107593
Guide to Pharmacology 505 (TRPP2)
PharmGKB PA33344
UniProt O75972 Q5W039 Q9P0L9 Q9UP35 Q9UPA2

Target Cross References - Domain

InterPro IPR003915 (PKD_2.)
IPR011992 (EF-hand-like_dom.)
IPR013122 (PKD1_2_channel.)
Pfam PF08016 (PKD_channel)
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