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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1628468
Target Type SINGLE PROTEIN
Preferred Name Transient receptor potential cation channel subfamily M member 5
Synonyms LTRPC5 | LTrpC-5 | LTrpC5 | Long transient receptor potential channel 5 | MLSN1- and TRP-related gene 1 protein | MTR1 | TRPM5 | Transient receptor potential cation channel subfamily M member 5
Organism Homo sapiens
Species Group No
Protein Target Classification
  • ion channel > voltage-gated ion channel > transient receptor potential channel

Target Components

Component Description Relationship Accession
Transient receptor potential cation channel subfamily M member 5 SINGLE PROTEIN Q9NZQ8

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000070985
Ensembl ENSG00000070985
GO Cellular Component GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0030425 (dendrite)
GO:0043025 (neuronal cell body)
GO Molecular Function GO:0005216 (ion channel activity)
GO:0005227 (calcium activated cation channel activity)
GO:0005244 (voltage-gated ion channel activity)
GO:0005267 (potassium channel activity)
GO:0005272 (sodium channel activity)
GO Biological Process GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0006812 (cation transport)
GO:0034220 (ion transmembrane transport)
GO:0034765 (regulation of ion transmembrane transport)
GO:0035725 (sodium ion transmembrane transport)
GO:0050909 (sensory perception of taste)
GO:0055085 (transmembrane transport)
GO:0070588 (calcium ion transmembrane transport)
GO:0071805 (potassium ion transmembrane transport)
GO:0098655 (cation transmembrane transport)
Wikipedia TRPM5

Target Cross References - Protein

Human Protein Atlas ENSG00000070985
Guide to Pharmacology 497
Open Targets ENSG00000070985
PharmGKB PA37869
Pharos Q9NZQ8 (Tbio)
Reactome R-HSA-3295583 (TRP channels.)
UniProt A6NHS0 Q52LU2 Q9NY34 Q9NZQ8

Target Cross References - Domain

InterPro IPR005821 (Ion_trans_dom.)
IPR029577 (TRPM5.)
Pfam PF00520 (Ion_trans)
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