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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1293298
Target Type SINGLE PROTEIN
Preferred Name Peripheral myelin protein 22
Synonyms GAS-3 | GAS3 | Growth arrest-specific protein 3 | PMP-22 | PMP22 | Peripheral myelin protein 22
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Peripheral myelin protein 22 SINGLE PROTEIN Q01453

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Expression Atlas ENSG00000109099
Ensembl ENSG00000109099
GO Cellular Component GO:0016021 (integral to membrane)
GO Biological Process GO:0007268 (synaptic transmission)
GO:0007422 (peripheral nervous system development)
Wikipedia Peripheral_myelin_protein_22

Target Cross References - Protein

CGD Roussy-Levy syndrome; Charcot-Marie-Tooth syndrome, type 1A; Charcot-Marie-Tooth syndrome with deafness (type 1E); Neuropathy, hereditary, with liability to pressurve palsies; Dejerine-Sottas disease; Neuropathy, inflammatory demyelinating
Human Protein Atlas ENSG00000109099
IntAct Q01453
PharmGKB PA33444
UniProt Q01453 Q8WV01

Target Cross References - Domain

InterPro IPR003936 (PMP22.)
IPR004031 (PMP22/EMP/MP20/Claudin.)
IPR004032 (PMP22_EMP_MP20.)
Pfam PF00822 (PMP22_Claudin)
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