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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1293193
Target Type SINGLE PROTEIN
Preferred Name Atrial natriuretic factor
Synonyms ANF | ANP | ANP | Atrial natriuretic factor | Atrial natriuretic peptide | CDD-ANF | CDP | Cardiodilatin-related peptide | NPPA | Natriuretic peptides A | PND | Prepronatriodilatin
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Natriuretic peptides A SINGLE PROTEIN P01160

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000175206
Ensembl ENSG00000175206
GO Cellular Component GO:0005576 (extracellular region)
GO Molecular Function GO:0005179 (hormone activity)
GO Biological Process GO:0006182 (cGMP biosynthetic process)
GO:0007168 (receptor guanylyl cyclase signaling pathway)
GO:0008217 (regulation of blood pressure)
GO:0050880 (regulation of blood vessel size)
Wikipedia Atrial_natriuretic_peptide

Target Cross References - Protein

CGD Atrial fibrillation, familial, 6
Human Protein Atlas ENSG00000175206
IntAct P01160
PharmGKB PA256
UniProt P01160 Q13766 Q5JZE1

Target Cross References - Domain

InterPro IPR000663 (Natr_peptide.)
IPR002407 (Natriuretic_peptide_atrial.)
Pfam PF00212 (ANP)

Target Cross References - Structure

PDBe 1YK0 3N57
CREDO 1YK0 3N57
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