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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1250411
Target Type SINGLE PROTEIN
Preferred Name Short transient receptor potential channel 5
Synonyms Short transient receptor potential channel 5 | TRP-5 | TRP5 | TRPC5 | Transient receptor protein 5 | TrpC5 | hTRP-5 | hTRP5
Organism Homo sapiens
Species Group No
Protein Target Classification
  • ion channel > voltage-gated ion channel > transient receptor potential channel

Target Components

Component Description Relationship Accession
Short transient receptor potential channel 5 SINGLE PROTEIN Q9UL62

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000072315
Ensembl ENSG00000072315
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0034704 (calcium channel complex)
GO Molecular Function GO:0005216 (ion channel activity)
GO:0005262 (calcium channel activity)
GO:0005515 (protein binding)
GO:0015279 (store-operated calcium channel activity)
GO:0070679 (inositol 1,4,5 trisphosphate binding)
GO Biological Process GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0006816 (calcium ion transport)
GO:0006828 (manganese ion transport)
GO:0007399 (nervous system development)
GO:0051480 (regulation of cytosolic calcium ion concentration)
GO:0055085 (transmembrane transport)
GO:0070588 (calcium ion transmembrane transport)
Wikipedia TRPC5

Target Cross References - Protein

Human Protein Atlas ENSG00000072315
IntAct Q9UL62
Guide to Pharmacology 490
Open Targets ENSG00000072315
PharmGKB PA37010
Pharos Q9UL62 (Tchem)
Reactome R-HSA-3295583 (TRP channels.)
R-HSA-418890 (Role of second messengers in netrin-1 signaling.)
UniProt B2RP53 O75233 Q5JXY8 Q9UL62 Q9Y514

Target Cross References - Domain

InterPro IPR002110 (Ankyrin_rpt.)
IPR002153 (TRPC_channel.)
IPR004729 (TRP_channel.)
IPR005461 (TRPC5_channel.)
IPR005821 (Ion_trans_dom.)
IPR013555 (TRP_dom.)
IPR020683 (Ankyrin_rpt-contain_dom.)
Pfam PF00520 (Ion_trans)
PF08344 (TRP_2)
PF12796 (Ank_2)
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