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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1250363
Target Type SINGLE PROTEIN
Preferred Name Protein max
Synonyms BHLHD4 | Class D basic helix-loop-helix protein 4 | MAX | Myc-associated factor X | Protein max | bHLHd4
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Protein max SINGLE PROTEIN P61244

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3301395 c-Myc/Max PROTEIN COMPLEX

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000125952
Ensembl ENSG00000125952
GO Cellular Component GO:0005634 (nucleus)
GO:0005654 (nucleoplasm)
GO:0005737 (cytoplasm)
GO:0030425 (dendrite)
GO:0071339 (MLL1 complex)
GO Molecular Function GO:0000978 (RNA polymerase II core promoter proximal region sequence-specific DNA binding)
GO:0000983 (transcription factor activity, RNA polymerase II core promoter sequence-specific)
GO:0003700 (sequence-specific DNA binding transcription factor activity)
GO:0003700 (transcription factor activity, sequence-specific DNA binding)
GO:0003712 (transcription cofactor activity)
GO:0003713 (transcription coactivator activity)
GO Biological Process GO:0006355 (regulation of transcription, DNA-dependent)
GO:0006366 (transcription from RNA polymerase II promoter)
Wikipedia MAX_(gene)

Target Cross References - Protein

CGD Pheochromocytoma
Human Protein Atlas ENSG00000125952
IntAct P61244
PharmGKB PA30656
TIMBAL Max
UniProt A8K265 A8K4G4 A8K824 P25912 P52163 P61244

Target Cross References - Domain

InterPro IPR001092 (HLH_DNA-bd_dom.)
IPR011598 (HLH_DNA-bd.)
IPR011598 (bHLH_dom.)
Pfam PF00010 (HLH)

Target Cross References - Structure

PDBe 1AN2 1HLO 1NKP 1NLW
CREDO 1AN2 1HLO 1NKP 1NLW
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