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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1075315
Preferred Name C-X-C chemokine receptor type 5
Synonyms BLR1 | Burkitt lymphoma receptor 1 | C-X-C chemokine receptor type 5 | CD_antigen=CD185 | CXC-R5 | CXCR-5 | CXCR5 | MDR-15 | MDR15 | Monocyte-derived receptor 15
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > peptide receptor (family a gpcr) > chemokine receptor > cxc chemokine receptor

Target Components

Component Description Relationship Accession
C-X-C chemokine receptor type 5 SINGLE PROTEIN P32302

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000160683
Ensembl ENSG00000160683
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0009897 (external side of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0005515 (protein binding)
GO:0016494 (C-X-C chemokine receptor activity)
GO Biological Process GO:0006935 (chemotaxis)
GO:0006955 (immune response)
GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0030595 (leukocyte chemotaxis)
GO:0032467 (positive regulation of cytokinesis)
GO:0042113 (B cell activation)
GO:0048535 (lymph node development)
GO:0070098 (chemokine-mediated signaling pathway)
Wikipedia CXCR5

Target Cross References - Protein

canSAR P32302
Human Protein Atlas ENSG00000160683
IntAct P32302
Guide to Pharmacology 72
Open Targets ENSG00000160683
PharmGKB PA162383046
Pharos P32302 (Tbio)
Reactome R-HSA-380108 (Chemokine receptors bind chemokines.)
R-HSA-418594 (G alpha (i) signalling events.)
UniProt P32302 Q14811

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR001053 (Chemokine_CXCR5.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)