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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2304404
Target Type SINGLE PROTEIN
Preferred Name Adenosine A1 receptor
Synonyms ADORA1 | Adenosine receptor A1
Organism Cavia porcellus
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Adenosine receptor A1 SINGLE PROTEIN P47745

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0043197 (dendritic spine)
GO:0045202 (synapse)
GO Molecular Function GO:0001609 (G-protein coupled adenosine receptor activity)
GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO Biological Process GO:0001973 (adenosine receptor signaling pathway)
GO:0002686 (negative regulation of leukocyte migration)
GO:0003093 (regulation of glomerular filtration)
GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0050728 (negative regulation of inflammatory response)
GO:0051930 (regulation of sensory perception of pain)
GO:0060079 (excitatory postsynaptic potential)
GO:0070256 (negative regulation of mucus secretion)
GO:1900453 (negative regulation of long term synaptic depression)

Target Cross References - Protein

UniProt P47745

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR001068 (Adeno_A1_rcpt.)
IPR001634 (Adenosn_rcpt.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
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