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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1650559
CHEMBL1650559
Compound Name PLAZOMICIN
ChEMBL Synonyms PLAZOMICIN SULFATE | PLAZOMICIN | ACHN-490
Max Phase 3
Trade Names
Molecular Formula C25H48N6O10

Additional synonyms for CHEMBL1650559 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CN[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3OC(=C ...
Download SMILES
Standard InChI InChI=1S/C25H48N6O10/c1-25(37)11-38-24(18(35)21(25)29-2)41-2 ...
Download InChI
Standard InChI Key IYDYFVUFSPQPPV-PEXOCOHZSA-N

Sources

  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL1650559

Molecule Features

CHEMBL1650559 compound icon
Drug Type:Natural Product-derived Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Unclassified Parenteral:Unclassified Topical:Unclassified Black Box:Unclassified Availability Type:Unclassified

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Renal InsufficiencyD0514371ClinicalTrials

Clinical Data

ClinicalTrials.gov PLAZOMICIN
The Cochrane Collaboration PLAZOMICIN

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
592.7 592.3432 -5.36 13 269.29 BASE


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
15 11 3 16 14 3


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
13.11 10.13 -3.83 -9.63 0 41 0.09

Structural Alerts

There are 4 structural alerts for CHEMBL1650559. To view alerts please click here.

Compound Cross References

ChemSpider ChemSpider:IYDYFVUFSPQPPV-PEXOCOHZSA-N

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1650559



DrugBank DB12615
FDA SRS LYO9XZ250J
IBM Patent System CC207A5FDB5BDA424027AD3B20726BC5
Nikkaji J3.052.262A
PDBe EDS
PubChem 42613186
PubChem: Drugs of the Future 123055433
PubChem: Thomson Pharma 81048177
SureChEMBL SCHEMBL11928040
ZINC ZINC000068150640

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/IYDYFVUFSPQPPV-PEXOCOHZSA-N spacer
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