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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL983
CHEMBL983
Compound Name SUCCINYLCHOLINE CHLORIDE
ChEMBL Synonyms ANECTINE | SUCCINYLCHOLINE CHLORIDE | SUXAMETHONE | Suxamethonium Chloride | SCOLINE | QUELICIN PRESERVATIVE FREE | SUCOSTRIN | QUELICIN
Max Phase 4 (Approved)
Trade Names ANECTINE | QUELICIN | QUELICIN PRESERVATIVE FREE | SCOLINE | SUCCINYLCHOLINE CHLORIDE | SUCOSTRIN | Suxamethonium Chloride
Molecular Formula C14H30Cl2N2O4

Additional synonyms for CHEMBL983 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES [Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C
Standard InChI InChI=1S/C14H30N2O4.2ClH/c1-15(2,3)9-11-19-13(17)7-8-14(18)2 ...
Download InChI
Standard InChI Key YOEWQQVKRJEPAE-UHFFFAOYSA-L

Sources

  • British National Formulary
  • DrugMatrix
  • Orange Book
  • PubChem BioAssays
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL983

Molecule Features

CHEMBL983 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Achiral Molecule Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:Y Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Muscle-type nicotinic acetylcholine receptor agonist Muscle-type nicotinic acetylcholine receptor ISBN

Clinical Data

ClinicalTrials.gov SUCCINYLCHOLINE CHLORIDE
The Cochrane Collaboration SUCCINYLCHOLINE CHLORIDE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Target Predictions

The two tables below display ChEMBL single-protein targets which are predicted to interact with CHEMBL983. A 1uM and 10 uM cut-off have been applied to ChEMBL bioactivity data used to generate the respective models and the yellow coloured rows correspond to genuine predictions, i.e. targets not included in the original training set for this compound.


1uM


ChEMBL_ID Target Name Organism Score
CHEMBL3762 Voltage-gated L-type calcium channel alpha-1C subunit Rattus norvegicus 0.990
CHEMBL4140 Epoxide hydratase Mus musculus 0.852
CHEMBL2026 Beta-lactamase AmpC Escherichia coli K-12 0.418
CHEMBL3510 Carbonic anhydrase XIV Homo sapiens 0.373
CHEMBL2001 Purinergic receptor P2Y12 Homo sapiens 0.373
CHEMBL1835 Thromboxane-A synthase Homo sapiens 0.336
CHEMBL276 Muscarinic acetylcholine receptor M1 Rattus norvegicus 0.307
CHEMBL2409 Epoxide hydratase Homo sapiens 0.258
CHEMBL3250 Lysophosphatidic acid receptor Edg-7 Homo sapiens 0.203



10uM


ChEMBL_ID Target Name Organism Score
CHEMBL3762 Voltage-gated L-type calcium channel alpha-1C subunit Rattus norvegicus 0.995
CHEMBL4140 Epoxide hydratase Mus musculus 0.877
CHEMBL1741179 Probable DNA dC->dU-editing enzyme APOBEC-3A Homo sapiens 0.564
CHEMBL2001 Purinergic receptor P2Y12 Homo sapiens 0.488
CHEMBL1835 Thromboxane-A synthase Homo sapiens 0.395
CHEMBL2026 Beta-lactamase AmpC Escherichia coli K-12 0.307
CHEMBL2409 Epoxide hydratase Homo sapiens 0.217

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
290.4 290.2195 0.27 9 52.6 -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
4 0 0 6 0 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - -5 -5 0 20 0.45

Structural Alerts

There are 5 structural alerts for CHEMBL983. To view alerts please click here.

Compound Cross References

ChemSpider ChemSpider:YOEWQQVKRJEPAE-UHFFFAOYSA-L
DailyMed succinylcholine chloride
PubChem SID: 144204820 SID: 170464625 SID: 50106980
Wikipedia Suxamethonium_chloride

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL983



ACToR 71-27-2 10168-63-5
Brenda 101506 44844 20528
ChEBI 61219
eMolecules 531639
EPA CompTox Dashboard DTXSID1023603
FDA SRS I9L0DDD30I
Mcule MCULE-2070369236
MolPort MolPort-003-939-350
PubChem 22475
PubChem: Thomson Pharma 14803458
SureChEMBL SCHEMBL41536

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/YOEWQQVKRJEPAE-UHFFFAOYSA-L spacer
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