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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL73416
CHEMBL73416
Compound Name SARIPIDEM
ChEMBL Synonyms Saripidem
Max Phase 0
Trade Names
Molecular Formula C19H20ClN3O

Additional synonyms for CHEMBL73416 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CCCC(=O)N(C)Cc1c(nc2ccccn12)c3ccc(Cl)cc3
Standard InChI InChI=1S/C19H20ClN3O/c1-3-6-18(24)22(2)13-16-19(14-8-10-15(2 ...
Download InChI
Standard InChI Key LIFDPEORUVTOCP-UHFFFAOYSA-N

Sources

  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL73416

Molecule Features

CHEMBL73416 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Achiral Molecule Prodrug:N Oral:Unclassified Parenteral:Unclassified Topical:Unclassified Black Box:Unclassified Availability Type:Unclassified

Clinical Data

ClinicalTrials.gov SARIPIDEM
The Cochrane Collaboration SARIPIDEM

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Target Predictions

The two tables below display ChEMBL single-protein targets which are predicted to interact with CHEMBL73416. A 1uM and 10 uM cut-off have been applied to ChEMBL bioactivity data used to generate the respective models and the yellow coloured rows correspond to genuine predictions, i.e. targets not included in the original training set for this compound.


1uM


ChEMBL_ID Target Name Organism Score
CHEMBL4552 Peripheral-type benzodiazepine receptor Rattus norvegicus 1.000
CHEMBL5742 Translocator protein Homo sapiens 0.729
CHEMBL2431 Serine/threonine-protein kinase AKT2 Homo sapiens 0.677

10uM


ChEMBL_ID Target Name Organism Score
CHEMBL4552 Peripheral-type benzodiazepine receptor Rattus norvegicus 1.000
CHEMBL2431 Serine/threonine-protein kinase AKT2 Homo sapiens 0.458
CHEMBL2608 Lysosomal alpha-glucosidase Homo sapiens 0.420
CHEMBL5742 Translocator protein Homo sapiens 0.401
CHEMBL1293226 Lysine-specific demethylase 4D-like Homo sapiens 0.344
CHEMBL2524 Alpha-galactosidase A Homo sapiens 0.237
CHEMBL215 Arachidonate 5-lipoxygenase Homo sapiens 0.222

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
341.8 341.1295 3.85 5 37.61 NEUTRAL


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
2 0 0 4 0 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- 6.37 4.2 4.19 3 24 0.71

Structural Alerts

There are no structural alerts for CHEMBL73416

Compound Cross References

ChemSpider ChemSpider:LIFDPEORUVTOCP-UHFFFAOYSA-N
Wikipedia Saripidem

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL73416



ACToR 103844-86-6
BindingDB 50290077
EPA CompTox Dashboard DTXSID60146110
FDA SRS 0J6174G60N
IBM Patent System ACC0A3A2445F73D5132E68116A150C95
Nikkaji J554.938H
PubChem 3058746
PubChem: Thomson Pharma 15397893
SureChEMBL SCHEMBL1061054

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/LIFDPEORUVTOCP-UHFFFAOYSA-N spacer
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