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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL607400
CHEMBL607400
Compound Name BRIVARACETAM
ChEMBL Synonyms Brivaracetam | UCB-34714
Max Phase 0
Trade Names
Molecular Formula C11H20N2O2

Additional synonyms for CHEMBL607400 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CCC[C@H]1CN([C@@H](CC)C(=O)N)C(=O)C1
Standard InChI InChI=1S/C11H20N2O2/c1-3-5-8-6-10(14)13(7-8)9(4-2)11(12)15/h ...
Download InChI
Standard InChI Key MSYKRHVOOPPJKU-BDAKNGLRSA-N

Molecule Features

CHEMBL607400 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Unclassified Parenteral:Unclassified Topical:Unclassified Black Box:Unclassified Availability Type:Unclassified

Clinical Data

Number of clinical trials registered at clinicaltrials.gov
Number of reviews at The Cochrane Collaboration
Number of entries at British National Formulary

Structural Alerts

There are no structural alerts for CHEMBL607400

Alternate Forms of Compound in ChEMBL


CHEMBL607400

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Target Predictions

The two tables below display ChEMBL single-protein targets which are predicted to interact with CHEMBL607400. A 1uM and 10 uM cut-off have been applied to ChEMBL bioactivity data used to generate the respective models and the yellow coloured rows correspond to genuine predictions, i.e. targets not included in the original training set for this compound.


1uM


ChEMBL_ID Target Name Organism Score
CHEMBL204 Thrombin Homo sapiens 0.465

10uM


ChEMBL_ID Target Name Organism Score
CHEMBL204 Thrombin Homo sapiens 0.475
CHEMBL4675 Tripeptidyl aminopeptidase Rattus norvegicus 0.202

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
212.3 212.1525 0.93 5 63.4 NEUTRAL


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
2 1 0 4 2 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - .67 .67 0 15 0.74

Compound Cross References

ChemSpider ChemSpider:MSYKRHVOOPPJKU-BDAKNGLRSA-N
Wikipedia Brivaracetam

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL607400



BindinDB 50422531
FDA SRS U863JGG2IA
IBM Patent System 041EFBCC3D02E3390EF1CA587099F11D
IBM Patents US20040116507 WO2008149163A2 EP2152274A1 US20100160299 EP2185535A1 US7465549 WO2010035032A1 WO2010025931A2 WO2009089494A2 US20070293476 EP2124920A1 WO2010074992A2 WO2006090275A1 EP2117559A2 EP1806339A1 US20070100150 US20050159475 WO2009144286A1 US7692028 US20090175939 EP1991212A1 WO2009086046A1 EP1925314A1 WO2008137960A1 WO2007027843A2 US7358276 US20100298245 EP2240022A2 US20100099735 WO2007031263A1 WO2010057869A1 WO2003094913A1 US20100125096 US20080153874 EP1756071B1 US20100004225 WO2008079720A1 US20100190752 US20100184861 US20060205674 WO2007144195A2 US20090318708 WO2007141002A1 US20090258865 US20080242646 WO2010044878A1 US20100015263 WO2008085927A2 US20100063148 WO2008038053A1 WO2009133387A1 US20090012313 EP1932009A2 US20080280862 US20090130216 WO2009054544A1 EP1625378A2 US20080097109 WO2010111622A2 US6806287 EP1731149A1 US6784197 US20030120080 US7655666 WO2010015029A1 WO2008027993A2 US7217826 WO2009018132A2 EP2254577A1 US20100240576 EP1926710A1 US20100286762 EP1958637A1 US20070299118 WO2010094535A1 WO2006108591A1 US20100240728 WO2005118561A1 US20100323016 US20090306225 EP2231594A2 US20070244143 WO2009081132A1 WO2010001179A2 US20090176865 EP1756071A1 WO2010132999A1 WO2010132693A2 WO2003030899A2 EP1993998A1 WO2009132050A2 EP2075011A2 US20050171188 US20100298336 US7564245 WO2009105853A2 US20080153836 US20090131508 WO2008118426A1 US20040204388
PubChem 9837243
PubChem: Drugs of the Future 22395457
PubChem: Thomson Pharma 14797750
SureChEMBL SCHEMBL122081

UniChem REST Service Call: https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/MSYKRHVOOPPJKU-BDAKNGLRSA-N spacer
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