ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Compound Report Card

Compound Name and Classification

Compound ID CHEMBL476960
CHEMBL476960
Compound Name VOGLIBOSE
ChEMBL Synonyms A-71100 | VOGLIBOSE | AO-128 | BASEN | GLUSTAT
Max Phase 3
Trade Names
Molecular Formula C10H21NO7

Additional synonyms for CHEMBL476960 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES OCC(CO)N[C@H]1C[C@](O)(CO)[C@@H](O)[C@H](O)[C@H]1O
Standard InChI InChI=1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16) ...
Download InChI
Standard InChI Key FZNCGRZWXLXZSZ-CIQUZCHMSA-N

Sources

  • PubChem BioAssays
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Alternate Forms of Compound in ChEMBL


CHEMBL476960

Molecule Features

CHEMBL476960 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Unclassified Parenteral:Unclassified Topical:Unclassified Black Box:Unclassified Availability Type:Unclassified

Mechanism of Action

Mechanism of Action ChEMBL Target References
Alpha glucosidase inhibitor Alpha glucosidase PubMed PubMed PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Diabetes MellitusD003920EFO:0000400diabetes mellitus3ATC
Diabetes Mellitus, Type 2D003924EFO:0001360type II diabetes mellitus3ClinicalTrials

Clinical Data

ClinicalTrials.gov VOGLIBOSE
The Cochrane Collaboration VOGLIBOSE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
267.3 267.1318 -4.49 5 153.64 NEUTRAL


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
8 8 1 8 8 1


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
13.26 6.84 -3.82 -3.92 0 18 0.25

Structural Alerts

There are 1 structural alerts for CHEMBL476960. To view alerts please click here.

Compound Cross References

ATC A - ALIMENTARY TRACT AND METABOLISM
A10 - DRUGS USED IN DIABETES
A10B - BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10BF - Alpha glucosidase inhibitors
A10BF03 - voglibose

ChemSpider ChemSpider:FZNCGRZWXLXZSZ-CIQUZCHMSA-N
PubChem SID: 144205773 SID: 170465993
Wikipedia Voglibose

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL476960



ACToR 83480-29-9
BindingDB 50263044
Brenda 6319
ChEBI 32300
ChemicalBook CB4481287
DrugBank DB04878
DrugCentral 2845
eMolecules 3715325 29539060
EPA CompTox Dashboard DTXSID2021442
FDA SRS S77P977AG8
Human Metabolome Database HMDB0015598
IBM Patent System 24D153F0EAB6413C3C1A0E998C88F38D
MolPort MolPort-003-987-271
Nikkaji J556.821H
PDBe VOG
PharmGKB PA164752433
PubChem 444020
PubChem: Drugs of the Future 12013776
PubChem: Thomson Pharma 15070756
SureChEMBL SCHEMBL5882
ZINC ZINC000003788703

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/FZNCGRZWXLXZSZ-CIQUZCHMSA-N spacer
spacer