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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL470670
CHEMBL470670
Compound Name LEVOMENTHOL
ChEMBL Synonyms LEVOMENTHOL | L-MENTHOL
Max Phase 0
Trade Names
Molecular Formula C10H20O

Additional synonyms for CHEMBL470670 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O
Standard InChI InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3 ...
Download InChI
Standard InChI Key NOOLISFMXDJSKH-KXUCPTDWSA-N

Sources

  • Patent Bioactivity Data
  • PubChem BioAssays
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL470670

Molecule Features

CHEMBL470670 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Unclassified Parenteral:Unclassified Topical:Unclassified Black Box:Unclassified Availability Type:Unclassified

Clinical Data

ClinicalTrials.gov LEVOMENTHOL
The Cochrane Collaboration LEVOMENTHOL

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Target Predictions

The two tables below display ChEMBL single-protein targets which are predicted to interact with CHEMBL470670. A 1uM and 10 uM cut-off have been applied to ChEMBL bioactivity data used to generate the respective models and the yellow coloured rows correspond to genuine predictions, i.e. targets not included in the original training set for this compound.


1uM


ChEMBL_ID Target Name Organism Score
CHEMBL5011 Transient receptor potential cation channel subfamily M member 8 Rattus norvegicus 1.000
CHEMBL3475 Plasminogen activator inhibitor-1 Homo sapiens 0.992
CHEMBL3614 Kappa opioid receptor Rattus norvegicus 0.941
CHEMBL237 Kappa opioid receptor Homo sapiens 0.934
CHEMBL3150 Vitamin D receptor Rattus norvegicus 0.932
CHEMBL5160 Transient receptor potential cation channel subfamily A member 1 Rattus norvegicus 0.843
CHEMBL2748 Sucrase-isomaltase Homo sapiens 0.797
CHEMBL3037 Cannabinoid CB1 receptor Mus musculus 0.792
CHEMBL1871 Androgen Receptor Homo sapiens 0.725
CHEMBL233 Mu opioid receptor Homo sapiens 0.614
CHEMBL4828 Synaptic vesicular amine transporter Rattus norvegicus 0.614
CHEMBL2878 Histone deacetylase 6 Mus musculus 0.526
CHEMBL3368 Glucocorticoid receptor Rattus norvegicus 0.492
CHEMBL3590 Hormone sensitive lipase Homo sapiens 0.385
CHEMBL4471 Thrombin Bos taurus 0.315
CHEMBL2179 Beta-glucocerebrosidase Homo sapiens 0.301
CHEMBL5373 Cannabinoid CB2 receptor Mus musculus 0.246



10uM


ChEMBL_ID Target Name Organism Score
CHEMBL5011 Transient receptor potential cation channel subfamily M member 8 Rattus norvegicus 1.000
CHEMBL5160 Transient receptor potential cation channel subfamily A member 1 Rattus norvegicus 1.000
CHEMBL3475 Plasminogen activator inhibitor-1 Homo sapiens 0.993
CHEMBL3262 Lanosterol synthase Rattus norvegicus 0.976
CHEMBL3614 Kappa opioid receptor Rattus norvegicus 0.972
CHEMBL237 Kappa opioid receptor Homo sapiens 0.947
CHEMBL3150 Vitamin D receptor Rattus norvegicus 0.941
CHEMBL4176 Alpha-L-fucosidase I Homo sapiens 0.909
CHEMBL3037 Cannabinoid CB1 receptor Mus musculus 0.843
CHEMBL2878 Histone deacetylase 6 Mus musculus 0.826
CHEMBL2748 Sucrase-isomaltase Homo sapiens 0.825
CHEMBL233 Mu opioid receptor Homo sapiens 0.754
CHEMBL1871 Androgen Receptor Homo sapiens 0.567
CHEMBL4828 Synaptic vesicular amine transporter Rattus norvegicus 0.555
CHEMBL3368 Glucocorticoid receptor Rattus norvegicus 0.440
CHEMBL2074 Maltase-glucoamylase Homo sapiens 0.399
CHEMBL1697668 Solute carrier organic anion transporter family member 1B1 Homo sapiens 0.394
CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase Homo sapiens 0.352
CHEMBL3305 Testis-specific androgen-binding protein Homo sapiens 0.277
CHEMBL4430 Cytochrome P450 17A1 Rattus norvegicus 0.272

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
156.3 156.1514 2.78 1 20.23 NEUTRAL


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
1 1 0 1 1 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - 3.22 3.22 0 11 0.62

Structural Alerts

There are no structural alerts for CHEMBL470670

Compound Cross References

ChemSpider ChemSpider:NOOLISFMXDJSKH-KXUCPTDWSA-N
PubChem SID: 144205173 SID: 144209021 SID: 144209117 SID: 144209806 SID: 144213316 SID: 144213345
Wikipedia Menthol

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL470670



BindingDB 50318482
ChEBI 15409
DrugBank DB00825
DrugCentral 934
eMolecules 484003
EPA CompTox Dashboard DTXSID1022180
FDA SRS BZ1R15MTK7
Guide to Pharmacology 2430
Human Metabolome Database HMDB0003352
IBM Patent System FCDD293BD1C9189E6D7649B3CA4CE6EB
KEGG Ligand C00400
LipidMaps LMPR0102090001
Mcule MCULE-9383663409 MCULE-8181548788
Metabolights MTBLC15409
Nikkaji J9.251G
NMRShiftDB 20182362
PharmGKB PA164776605
PubChem 16666
PubChem: Thomson Pharma 15219325 15146951
Rhea 15409
SureChEMBL SCHEMBL4613
ZINC ZINC000001482164

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/NOOLISFMXDJSKH-KXUCPTDWSA-N spacer
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