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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL2221250
CHEMBL2221250
Compound Name CAPREOMYCIN
ChEMBL Synonyms 34977 | CAPASTAT SULFATE | Capreomycin | CAPREOMYCIN SULFATE | CAPASTAT
Max Phase 4 (Approved)
Trade Names CAPASTAT SULFATE | CAPASTAT
Molecular Formula C50H88N28O15

Additional synonyms for CHEMBL2221250 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES C[C@@H]1NC(=O)[C@@H](N)CNC(=O)[C@@H](NC(=O)\C(=C\NC(=O)N)\NC ...
Download SMILES
Standard InChI InChI=1S/C25H44N14O8.C25H44N14O7/c26-4-1-2-11(27)6-17(41)32- ...
Download InChI
Standard InChI Key VCOPTHOUUNAYKQ-DAOVIKHBSA-N

Sources

  • British National Formulary
  • Orange Book
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Alternate Forms of Compound in ChEMBL


CHEMBL2221250

Molecule Features

CHEMBL2221250 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Unknown Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:Y Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
70S ribosome inhibitor 70S ribosome PubMed PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
OsteomyelitisD010019EFO:0003102osteomyelitis0ClinicalTrials

Clinical Data

ClinicalTrials.gov CAPREOMYCIN
The Cochrane Collaboration CAPREOMYCIN

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
1321.4 1320.6984 - - - -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
- - - - - -


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - - - - - -0

Structural Alerts

There are no structural alerts for CHEMBL2221250

Compound Cross References

ATC J - ANTIINFECTIVES FOR SYSTEMIC USE
J04 - ANTIMYCOBACTERIALS
J04A - DRUGS FOR TREATMENT OF TUBERCULOSIS
J04AB - Antibiotics
J04AB30 - capreomycin

ChemSpider ChemSpider:VCOPTHOUUNAYKQ-DAOVIKHBSA-N
DailyMed capreomycin sulfate

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL2221250



PubChem 73952296

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/VCOPTHOUUNAYKQ-DAOVIKHBSA-N spacer
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