ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Compound Report Card

Compound Name and Classification

Compound ID CHEMBL2070241
CHEMBL2070241
Compound Name BREMELANOTIDE
ChEMBL Synonyms BREMELANOTIDE | PT-141
Max Phase 3
Trade Names
Molecular Formula C50H68N14O10

Additional synonyms for CHEMBL2070241 found using NCI Chemical Identifier Resolver

Sources

  • AstraZeneca Deposited Data
  • Clinical Candidates
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Molecule Features

CHEMBL2070241 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Unclassified Parenteral:Unclassified Topical:Unclassified Black Box:Unclassified Availability Type:Unclassified

Mechanism of Action

Mechanism of Action ChEMBL Target References
Melanocortin receptor 1 agonist Melanocortin receptor 1 PubMed PubMed
Melanocortin receptor 3 agonist Melanocortin receptor 3 PubMed PubMed
Melanocortin receptor 4 agonist Melanocortin receptor 4 PubMed PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
SEXUAL DYSFUNCTION, PHYSIOLOGICALD012735EFO:0004714SEXUAL DYSFUNCTION3ClinicalTrials

Clinical Data

ClinicalTrials.gov BREMELANOTIDE
The Cochrane Collaboration BREMELANOTIDE

HELM Notation

CHEMBL2070241 HELM Notation
PEPTIDE1{H.[dF].R.W.K}|PEPTIDE2{[ac].[Nle].D}$PEPTIDE2,PEPTIDE1,3:R2-1:R1|PEPTIDE2,PEPTIDE1,3:R3-5:R3$$$

The ChEMBL HELM monomer library is available to download here.

For more details about HELM Notation, please visit the HELM Homepage.

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Compound Cross References

ChemSpider ChemSpider:FFHBJDQSGDNCIV-MFVUMRCOSA-N

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL2070241



BindingDB 50389769
DrugBank DB11653
eMolecules 30100206
FDA SRS 6Y24O4F92S
MolPort MolPort-009-194-183
PubChem 9941379
PubChem: Thomson Pharma 14914581
SureChEMBL SCHEMBL13574795

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/FFHBJDQSGDNCIV-MFVUMRCOSA-N spacer
spacer