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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1685
Compound Name DEZOCINE
ChEMBL Synonyms WY-16,225 | DALGAN | DEZOCINE
Max Phase 4 (Approved)
Trade Names DALGAN
Molecular Formula C16H23NO

Additional synonyms for CHEMBL1685 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES C[C@@]12CCCCC[C@@H](Cc3ccc(O)cc13)[C@@H]2N
Standard InChI InChI=1S/C16H23NO/c1-16-8-4-2-3-5-12(15(16)17)9-11-6-7-13(18 ...
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  • Orange Book
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Alternate Forms of Compound in ChEMBL


Molecule Features

CHEMBL1685 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Discontinued

Mechanism of Action

Mechanism of Action ChEMBL Target References
Kappa opioid receptor antagonist Kappa opioid receptor ISBN PubMed
Mu opioid receptor partial agonist Mu opioid receptor ISBN PubMed


MESH Heading MESH ID EFO ID EFO Term Max phase for indication References

Clinical Data DEZOCINE
The Cochrane Collaboration DEZOCINE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Target Predictions

The two tables below display ChEMBL single-protein targets which are predicted to interact with CHEMBL1685. A 1uM and 10 uM cut-off have been applied to ChEMBL bioactivity data used to generate the respective models and the yellow coloured rows correspond to genuine predictions, i.e. targets not included in the original training set for this compound.


ChEMBL_ID Target Name Organism Score
CHEMBL233 Mu opioid receptor Homo sapiens 1.000
CHEMBL236 Delta opioid receptor Homo sapiens 1.000
CHEMBL3952 Kappa opioid receptor Cavia porcellus 1.000
CHEMBL237 Kappa opioid receptor Homo sapiens 1.000
CHEMBL4354 Mu opioid receptor Cavia porcellus 1.000
CHEMBL4329 Kappa opioid receptor Mus musculus 1.000
CHEMBL270 Mu opioid receptor Rattus norvegicus 1.000
CHEMBL287 Sigma opioid receptor Homo sapiens 1.000
CHEMBL3602 Sigma opioid receptor Rattus norvegicus 1.000
CHEMBL3222 Delta opioid receptor Mus musculus 1.000
CHEMBL2858 Mu opioid receptor Mus musculus 0.999
CHEMBL3614 Kappa opioid receptor Rattus norvegicus 0.993
CHEMBL3041 Mu opioid receptor Bos taurus 0.920
CHEMBL220 Acetylcholinesterase Homo sapiens 0.652
CHEMBL3465 Sigma opioid receptor Mus musculus 0.628
CHEMBL269 Delta opioid receptor Rattus norvegicus 0.621
CHEMBL242 Estrogen receptor beta Homo sapiens 0.555