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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1614854
CHEMBL1614854
Compound Name DEXTROSE
ChEMBL Synonyms DEXTROGEL | GSF-SYRUP | GLUCOSE | DEXTRO ENERGY | YOURGLUCO | CAPD | GAMBROSOL | CLINTEC | RAPILOSE | DEXTROSE
Max Phase 4 (Approved)
Trade Names CLINTEC | RAPILOSE | DEXTROGEL | GSF-SYRUP | YOURGLUCO | DEXTRO ENERGY | GAMBROSOL | CAPD
Molecular Formula C6H12O6

Additional synonyms for CHEMBL1614854 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
Standard InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2 ...
Download InChI
Standard InChI Key WQZGKKKJIJFFOK-VFUOTHLCSA-N

Sources

  • British National Formulary
  • Orange Book
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Alternate Forms of Compound in ChEMBL


CHEMBL1614854

Molecule Features

CHEMBL1614854 compound icon
Drug Type:Natural Product-derived Rule of Five:Y First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Clinical Data

ClinicalTrials.gov DEXTROSE
The Cochrane Collaboration DEXTROSE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Target Predictions

The two tables below display ChEMBL single-protein targets which are predicted to interact with CHEMBL1614854. A 1uM and 10 uM cut-off have been applied to ChEMBL bioactivity data used to generate the respective models and the yellow coloured rows correspond to genuine predictions, i.e. targets not included in the original training set for this compound.


1uM


ChEMBL_ID Target Name Organism Score
CHEMBL3884 Sodium/glucose cotransporter 2 Homo sapiens 1.000
CHEMBL4837 Adhesin protein fimH Escherichia coli K-12 1.000
CHEMBL318 Adenosine A1 receptor Rattus norvegicus 1.000
CHEMBL5921 Bifunctional protein NCOAT Homo sapiens 1.000
CHEMBL1770047 Low affinity sodium-glucose cotransporter Homo sapiens 1.000
CHEMBL1997 Equilibrative nucleoside transporter 1 Homo sapiens 1.000
CHEMBL4979 Sodium/glucose cotransporter 1 Homo sapiens 1.000
CHEMBL302 Adenosine A2a receptor Rattus norvegicus 1.000
CHEMBL226 Adenosine A1 receptor Homo sapiens 1.000
CHEMBL3360 Adenosine A3 receptor Rattus norvegicus 1.000
CHEMBL2304404 Adenosine A1 receptor Cavia porcellus 1.000
CHEMBL1781 DNA topoisomerase I Homo sapiens 1.000
CHEMBL256 Adenosine A3 receptor Homo sapiens 1.000
CHEMBL3589 Adenosine kinase Homo sapiens 1.000
CHEMBL4975 Adenosine A1 receptor Bos taurus 0.996
CHEMBL2864 6-O-methylguanine-DNA methyltransferase Homo sapiens 0.994
CHEMBL1293237 Bloom syndrome protein Homo sapiens 0.993
CHEMBL4176 Alpha-L-fucosidase I Homo sapiens 0.984
CHEMBL3114 Sucrase-isomaltase Rattus norvegicus 0.969
CHEMBL4398 Purinergic receptor P2Y2 Homo sapiens 0.965



10uM


ChEMBL_ID Target Name Organism Score
CHEMBL3884 Sodium/glucose cotransporter 2 Homo sapiens 1.000
CHEMBL4837 Adhesin protein fimH Escherichia coli K-12 1.000
CHEMBL4696 Glycogen phosphorylase, muscle form Oryctolagus cuniculus 1.000
CHEMBL318 Adenosine A1 receptor Rattus norvegicus 1.000
CHEMBL4979 Sodium/glucose cotransporter 1 Homo sapiens 1.000
CHEMBL2982 Adenosine kinase Toxoplasma gondii 1.000
CHEMBL5921 Bifunctional protein NCOAT Homo sapiens 1.000
CHEMBL1770047 Low affinity sodium-glucose cotransporter Homo sapiens 1.000
CHEMBL1997 Equilibrative nucleoside transporter 1 Homo sapiens 1.000
CHEMBL302 Adenosine A2a receptor Rattus norvegicus 1.000
CHEMBL1973 Tyrosinase Homo sapiens 1.000
CHEMBL3360 Adenosine A3 receptor Rattus norvegicus 1.000
CHEMBL3513 Acidic alpha-glucosidase Rattus norvegicus 1.000
CHEMBL3589 Adenosine kinase Homo sapiens 1.000
CHEMBL4518 Purinergic receptor P2Y14 Homo sapiens 1.000
CHEMBL256 Adenosine A3 receptor Homo sapiens 1.000
CHEMBL226 Adenosine A1 receptor Homo sapiens 1.000
CHEMBL1781 DNA topoisomerase I Homo sapiens 0.999
CHEMBL2304404 Adenosine A1 receptor Cavia porcellus 0.999
CHEMBL4176 Alpha-L-fucosidase I Homo sapiens 0.999

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
180.2 180.0634 -3.22 1 110.38 NEUTRAL


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
6 5 0 6 5 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
12.12 - -2.49 -2.49 0 12 0.29

Structural Alerts

There are 1 structural alerts for CHEMBL1614854. To view alerts please click here.

Compound Cross References

ATC V - VARIOUS
V06 - GENERAL NUTRIENTS
V06D - OTHER NUTRIENTS
V06DC - Carbohydrates
V06DC01 - glucose

B - BLOOD AND BLOOD FORMING ORGANS
B05 - BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05C - IRRIGATING SOLUTIONS
B05CX - Other irrigating solutions
B05CX01 - glucose

C - CARDIOVASCULAR SYSTEM
C05 - VASOPROTECTIVES
C05B - ANTIVARICOSE THERAPY
C05BB - Sclerosing agents for local injection
C05BB56 - glucose, combinations

V - VARIOUS
V04 - DIAGNOSTIC AGENTS
V04C - OTHER DIAGNOSTIC AGENTS
V04CA - Tests for diabetes
V04CA02 - glucose

ChemSpider ChemSpider:WQZGKKKJIJFFOK-VFUOTHLCSA-N
DailyMed dextrose

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1614854



ACToR 108942-17-2
BindingDB 50240803
Brenda 106573 16259 1773 49223 43858 96
ChEBI 15903
DrugBank DB02379
DrugCentral 845
eMolecules 6842964
EPA CompTox Dashboard DTXSID70883403
FDA SRS J4R00M814D
Human Metabolome Database HMDB0000516
IBM Patent System 806BD1A26418ADDBB47402FD57A2DBE6
KEGG Ligand C00221
Mcule MCULE-4260589665
Metabolights MTBLC15903
MolPort MolPort-006-111-449
Nikkaji J44.213E
NMRShiftDB 20027186
PDBe BGC
PubChem 64689
PubChem: Thomson Pharma 15195159
Rhea 15903
SureChEMBL SCHEMBL25601
ZINC ZINC000003833800

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/WQZGKKKJIJFFOK-VFUOTHLCSA-N spacer
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