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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL159298
CHEMBL159298
Compound Name RIPAZEPAM
ChEMBL Synonyms RIPAZEPAM | CL-683
Max Phase 0
Trade Names
Molecular Formula C15H16N4O

Additional synonyms for CHEMBL159298 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CCn1nc(C)c2NC(=O)CN=C(c3ccccc3)c12
Standard InChI InChI=1S/C15H16N4O/c1-3-19-15-13(10(2)18-19)17-12(20)9-16-14 ...
Download InChI
Standard InChI Key YFHYNLHGFKXAIQ-UHFFFAOYSA-N

Sources

  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL159298

Molecule Features

CHEMBL159298 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Achiral Molecule Prodrug:N Oral:Unclassified Parenteral:Unclassified Topical:Unclassified Black Box:Unclassified Availability Type:Unclassified

Clinical Data

ClinicalTrials.gov RIPAZEPAM
The Cochrane Collaboration RIPAZEPAM

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Target Predictions

The two tables below display ChEMBL single-protein targets which are predicted to interact with CHEMBL159298. A 1uM and 10 uM cut-off have been applied to ChEMBL bioactivity data used to generate the respective models and the yellow coloured rows correspond to genuine predictions, i.e. targets not included in the original training set for this compound.


10uM


ChEMBL_ID Target Name Organism Score
CHEMBL1827 Phosphodiesterase 5A Homo sapiens 0.254

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
268.3 268.1324 1.87 2 59.28 NEUTRAL


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
3 1 0 5 1 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
12.96 1.35 .58 .58 2 20 0.9

Structural Alerts

There are no structural alerts for CHEMBL159298

Compound Cross References

ChemSpider ChemSpider:YFHYNLHGFKXAIQ-UHFFFAOYSA-N
Wikipedia Ripazepam

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL159298



ACToR 26308-28-1
ChEBI 82529
DrugCentral 2386
eMolecules 3715250
EPA CompTox Dashboard DTXSID1021245
FDA SRS 92000WH9C9
KEGG Ligand C19518
Nikkaji J20.440D
PubChem 33474
PubChem: Drugs of the Future 22395422
PubChem: Thomson Pharma 15269461
SureChEMBL SCHEMBL636179

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/YFHYNLHGFKXAIQ-UHFFFAOYSA-N spacer
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