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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1472
CHEMBL1472
Compound Name PROTIRELIN
ChEMBL Synonyms A-38579 | Protirelin Tartrate | Synthetic Trh | ABBOTT-38579 | Thyrel Trh | Protirelin | Thypinone | Lopremone
Max Phase 4 (Approved)
Trade Names Thyrel Trh | Thypinone
Molecular Formula C16H22N6O4

Additional synonyms for CHEMBL1472 found using NCI Chemical Identifier Resolver

Mechanism of Action

Mechanism of Action ChEMBL Target References
Thyrotropin-releasing hormone receptor agonist Thyrotropin-releasing hormone receptor DailyMed PubMed

Molecule Features

CHEMBL1472 compound icon
Drug Type:Oligopeptide Rule of Five:Y First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Discontinued

Clinical Data

Number of clinical trials registered at clinicaltrials.gov
Number of reviews at The Cochrane Collaboration
Number of entries at British National Formulary

HELM Notation

CHEMBL1472 HELM Notation
PEPTIDE1{[Glp].H.P.[am]}$$$$

The ChEMBL HELM monomer library is available to download here.

For more details about HELM Notation, please visit the HELM Homepage.

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Compound Cross References

ATC V - VARIOUS
V04 - DIAGNOSTIC AGENTS
V04C - OTHER DIAGNOSTIC AGENTS
V04CJ - Tests for thyreoidea function
V04CJ02 - protirelin

ChemSpider ChemSpider:XNSAINXGIQZQOO-SRVKXCTJSA-N
DailyMed protirelin
PubChem SID: 144205492 SID: 29216304
Wikipedia Thyrotropin-releasing_hormone

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1472



ACToR 24305-27-9
BindingDB 50072394
ChEBI 35940
DrugBank DB09421
eMolecules 5750666
EPA CompTox Dashboard DTXSID0023533
FDA SRS 5Y5F15120W
Guide to Pharmacology 2139
Human Metabolome Database HMDB60080
IBM Patent System E32867DB4A6DBE59F2A47776ED53DEF6
KEGG Ligand C03958
MolPort MolPort-006-124-300
Nikkaji J3.473H
PubChem 638678
PubChem: Thomson Pharma 16136709 14926032
Recon C03958
SureChEMBL SCHEMBL33419
ZINC ZINC04096261

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/XNSAINXGIQZQOO-SRVKXCTJSA-N spacer
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