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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1255800
CHEMBL1255800
Compound Name FIDAXOMICIN
ChEMBL Synonyms OPT-80 | Dificid | PAR-101 | Fidaxomicin
Max Phase 4 (Approved)
Trade Names Dificid
Molecular Formula C52H74Cl2O18

Additional synonyms for CHEMBL1255800 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CC[C@H]1\C=C(/C)\[C@@H](O)C\C=C\C=C(/CO[C@@H]2O[C@H](C)[C@@H ...
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Standard InChI InChI=1S/C52H74Cl2O18/c1-13-30-22-26(6)33(56)18-16-15-17-31( ...
Download InChI
Standard InChI Key ZVGNESXIJDCBKN-UUEYKCAUSA-N

Mechanism of Action

Mechanism of Action ChEMBL Target References
DNA-directed RNA polymerase inhibitor DNA-directed RNA polymerase DailyMed

Molecule Features

CHEMBL1255800 compound icon
Drug Type:Natural Product Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:N Availability Type:Prescription-only

Clinical Data

Number of clinical trials registered at clinicaltrials.gov
Number of reviews at The Cochrane Collaboration
Number of entries at British National Formulary

Structural Alerts

There are no structural alerts for CHEMBL1255800

Alternate Forms of Compound in ChEMBL


CHEMBL1255800

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
1058 1056.4252 - - - -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
- - - - - -


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - - - - - -0

Compound Cross References

ATC A - ALIMENTARY TRACT AND METABOLISM
A07 - ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE
A07A - INTESTINAL ANTIINFECTIVES
A07AA - Antibiotics
A07AA12 - fidaxomicin

ChemSpider ChemSpider:ZVGNESXIJDCBKN-UUEYKCAUSA-N
DailyMed fidaxomicin
Wikipedia Fidaxomicin

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1255800



FDA SRS Z5N076G8YQ
PubChem 10034073
PubChem: Drugs of the Future 22395184
PubChem: Thomson Pharma 15015656
SureChEMBL SCHEMBL10000818

UniChem REST Service Call: https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/ZVGNESXIJDCBKN-UUEYKCAUSA-N spacer
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