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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1201835
CHEMBL1201835
Compound Name USTEKINUMAB
ChEMBL Synonyms CNTO-1275 | STELARA | USTEKINUMAB | USTEKINUMAB | STELERA | TT-20
Max Phase 4 (Approved)
Trade Names STELERA | STELARA

Sources

  • British National Formulary
  • Clinical Candidates
  • Manually Added Drugs
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL1201835 compound icon
Drug Type:Antibody Rule of Five:N First In Class:Y Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Interleukin-12 inhibitor Interleukin-12 DailyMed
Interleukin-23 inhibitor Interleukin-23 DailyMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Lupus Erythematosus, SystemicD008180EFO:0002690systemic lupus erythematosus2ClinicalTrials
PsoriasisD011565EFO:0000676psoriasis4ClinicalTrials
DailyMed
Giant Cell ArteritisD013700EFO:1001209temporal arteritis1ClinicalTrials
Liver Cirrhosis, BiliaryD008105EFO:1001486primary biliary cirrhosis2ClinicalTrials
SarcoidosisD012507Orphanet:797Sarcoidosis2ClinicalTrials
Arthritis, PsoriaticD015535EFO:0003778psoriatic arthritis4ClinicalTrials
DailyMed
Dermatitis, AtopicD003876EFO:0000274atopic eczema2ClinicalTrials
Graft vs Host DiseaseD006086EFO:0004599acute graft vs. host disease2ClinicalTrials
Hidradenitis SuppurativaD017497EFO:1000710hidradenitis suppurativa2ClinicalTrials
Spondylitis, AnkylosingD013167EFO:0003898ankylosing spondylitis3ClinicalTrials
Arthritis, RheumatoidD001172EFO:0000685rheumatoid arthritis2ClinicalTrials
Immune System DiseasesD007154EFO:0000540immune system disease4ATC
UveitisD014605EFO:1001231uveitis2ClinicalTrials
Crohn DiseaseD003424EFO:0000384Crohn's disease3ClinicalTrials
Multiple SclerosisD009103EFO:0003885multiple sclerosis2ClinicalTrials
Diabetes Mellitus, Type 1D003922EFO:0001359type I diabetes mellitus2ClinicalTrials
Behcet SyndromeD001528EFO:0003780Behcet's syndrome2ClinicalTrials
Colitis, UlcerativeD003093EFO:0000729ulcerative colitis3ClinicalTrials

Clinical Data

ClinicalTrials.gov USTEKINUMAB
The Cochrane Collaboration USTEKINUMAB

Compound Cross References

ATC L - ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L04 - IMMUNOSUPPRESSANTS
L04A - IMMUNOSUPPRESSANTS
L04AC - Interleukin inhibitors
L04AC05 - ustekinumab

ChemSpider ChemSpider Identifier not yet assigned
DailyMed ustekinumab
Wikipedia Ustekinumab
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