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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1201208
CHEMBL1201208
Compound Name PHENMETRAZINE
ChEMBL Synonyms PHENMETRAZINE HYDROCHLORIDE | PRELUDIN | PHENMETRALINE HYDROCHLORIDE | Phenmetrazine chloride
Max Phase 4 (Approved)
Trade Names PRELUDIN
Molecular Formula C11H15NO

Additional synonyms for CHEMBL1201208 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CC1NCCOC1c2ccccc2
Standard InChI InChI=1S/C11H15NO/c1-9-11(13-8-7-12-9)10-5-3-2-4-6-10/h2-6,9 ...
Download InChI
Standard InChI Key OOBHFESNSZDWIU-UHFFFAOYSA-N

Alternate Forms of Compound in ChEMBL


CHEMBL1201208

Molecule Features

CHEMBL1201208 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Racemic Mixture Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:N Availability Type:Discontinued

Mechanism of Action

Mechanism of Action ChEMBL Target References
Dopamine transporter inhibitor Dopamine transporter PubMed
Norepinephrine transporter inhibitor Norepinephrine transporter PubMed

Clinical Data

Number of clinical trials registered at clinicaltrials.gov
Number of reviews at The Cochrane Collaboration
Number of entries at British National Formulary

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
177.2 177.1154 1.46 1 21.26 ACID


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
2 1 0 2 1 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
1.01 - -1.41 -6.14 1 13 0.7

Structural Alerts

There are no structural alerts for CHEMBL1201208

Compound Cross References

ChemSpider ChemSpider:OOBHFESNSZDWIU-UHFFFAOYSA-N
Wikipedia Phenmetrazine

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1201208



ACToR 134-49-6
ChEBI 8067
DrugBank DB00830
DrugCentral 2133
eMolecules 975916
EPA CompTox Dashboard DTXSID5023455
Human Metabolome Database HMDB14968
IBM Patent System C09C9C3ABE385BD04AD9586128CD78F7
KEGG Ligand C07432
Mcule MCULE-3684334876
Nikkaji J5.596D
PharmGKB PA164747188
PubChem 4762
PubChem: Thomson Pharma 15322006
SureChEMBL SCHEMBL33984

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/OOBHFESNSZDWIU-UHFFFAOYSA-N spacer
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