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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1201201
CHEMBL1201201
Compound Name METHAMPHETAMINE
ChEMBL Synonyms DESOXYN | METHAMPEX | Methamphetamine | DESOXYEPHEDRINE HYDROCHLORIDE | METHAMPHETAMINE HYDROCHLORIDE | METAMFETAMINE
Max Phase 4 (Approved)
Withdrawn Yes
Trade Names DESOXYN | METHAMPEX | METHAMPHETAMINE HYDROCHLORIDE
Molecular Formula C10H15N

Additional synonyms for CHEMBL1201201 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CN[C@@H](C)Cc1ccccc1
Standard InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2, ...
Download InChI
Standard InChI Key MYWUZJCMWCOHBA-VIFPVBQESA-N

Sources

  • British National Formulary
  • Gene Expression Atlas Compounds
  • Orange Book
  • PubChem BioAssays
  • Scientific Literature
  • TP-search Transporter Database
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification
  • Withdrawn Drugs

Alternate Forms of Compound in ChEMBL


CHEMBL1201201

Molecule Features

CHEMBL1201201 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:Y Availability Type:Prescription-only

Withdrawal Information

Year
Country United States
Reason

Mechanism of Action

Mechanism of Action ChEMBL Target References
Monoamine transporter inhibitor Monoamine transporter ISBN

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
AMPHETAMINE-RELATED DISORDERSD019969EFO:0004701METAMPHETAMINE DEPENDENCE0ClinicalTrials

Clinical Data

ClinicalTrials.gov METHAMPHETAMINE
The Cochrane Collaboration METHAMPHETAMINE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
149.2 149.1204 2.07 3 12.03 BASE


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
1 1 0 1 1 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- 10.38 2.2 -.54 1 11 0.69

Structural Alerts

There are no structural alerts for CHEMBL1201201

Compound Cross References

ATC N - NERVOUS SYSTEM
N06 - PSYCHOANALEPTICS
N06B - PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
N06BA - Centrally acting sympathomimetics
N06BA03 - metamfetamine

ChemSpider ChemSpider:MYWUZJCMWCOHBA-VIFPVBQESA-N
DailyMed methamphetamine hydrochloride
Wikipedia Methamphetamine

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1201201



ACToR 139-47-9 537-46-2
Atlas methamphetamine
BindingDB 50359499
ChEBI 6809
DrugBank DB01577
DrugCentral 1732
eMolecules 36759798
EPA CompTox Dashboard DTXSID8037128
FDA SRS 44RAL3456C
Human Metabolome Database HMDB0015517
IBM Patent System 52CE4C11905691869553E6F5E824BA48
KEGG Ligand C07164
Nikkaji J6.362B
PDBe B40
PharmGKB PA450403
PubChem 10836
PubChem: Thomson Pharma 15194699
SureChEMBL SCHEMBL42615
ZINC ZINC000006021043

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/MYWUZJCMWCOHBA-VIFPVBQESA-N spacer
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