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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1200689
CHEMBL1200689
Compound Name NITRIC OXIDE
ChEMBL Synonyms Nitric Oxide | Inomax
Max Phase 4 (Approved)
Trade Names Inomax
Molecular Formula NO

Additional synonyms for CHEMBL1200689 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES O=[N]
Standard InChI InChI=1S/NO/c1-2
Standard InChI Key MWUXSHHQAYIFBG-UHFFFAOYSA-N

Indications for CHEMBL1200689

MESH Heading MESH ID EFO ID EFO Term Max phase for indication
ANEMIA, SICKLE CELLD000755Orphanet:232SICKLE CELL ANEMIA2
BRONCHIOLITISD001988HP:0011950BRONCHIOLITIS1
BRONCHOPULMONARY DYSPLASIAD001997Orphanet:70589BRONCHOPULMONARY DYSPLASIA3
CYSTIC FIBROSISD003550Orphanet:586CYSTIC FIBROSIS2
HEART FAILURED006333EFO:0000373CONGESTIVE HEART FAILURE2
HYPERTENSION, PULMONARYD006976EFO:0001361PULMONARY HYPERTENSION2
LEISHMANIASIS, CUTANEOUSD016773EFO:0005046CUTANEOUS LEISHMANIASIS3
LUNG DISEASESD008171EFO:0003818LUNG DISEASE2
MALARIAD008288EFO:0001068MALARIA2
MYOCARDIAL INFARCTIOND009203EFO:0000612MYOCARDIAL INFARCTION2
NEURALGIAD009437EFO:0005762NEUROPATHIC PAIN2
PRESSURE ULCERD003668HP:0012399PRESSURE ULCER1
PULMONARY EMBOLISMD011655EFO:0003827PULMONARY EMBOLISM2
REPERFUSION INJURYD015427EFO:0002687ISCHEMIA REPERFUSION INJURY3
SEPSISD018805EFO:0001420SEPSIS3
SEVERE ACUTE RESPIRATORY SYNDROMED045169EFO:0000694SEVERE ACUTE RESPIRATORY SYNDROME3
SKIN ULCERD012883HP:0200042SKIN ULCER2

Molecule Features

CHEMBL1200689 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Achiral Molecule Prodrug:N Oral:N Parenteral:N Topical:Y Black Box:N Availability Type:Prescription-only

Clinical Data

Number of clinical trials registered at clinicaltrials.gov
Number of reviews at The Cochrane Collaboration
Number of entries at British National Formulary

Structural Alerts

There are no structural alerts for CHEMBL1200689

Alternate Forms of Compound in ChEMBL


CHEMBL1200689

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
30 29.998 0.4 0 39.37 -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
2 0 0 2 0 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - .74 .74 0 2 0.39

Compound Cross References

ATC R - RESPIRATORY SYSTEM
R07 - OTHER RESPIRATORY SYSTEM PRODUCTS
R07A - OTHER RESPIRATORY SYSTEM PRODUCTS
R07AX - Other respiratory system products
R07AX01 - nitric oxide

ChemSpider ChemSpider:MWUXSHHQAYIFBG-UHFFFAOYSA-N
DailyMed nitric oxide
Wikipedia Nitric_oxide Nitroxyl

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1200689



ChEBI 16480
DrugBank DB00435
DSSTox DTXSID1020938
eMolecules 17497970
FDA SRS 31C4KY9ESH
Human Metabolome Database HMDB03378
KEGG Ligand C00533
Nikkaji J415.432K J1.313.254B
PharmGKB PA450635
PubChem 145068
PubChem: Thomson Pharma 15170299
Recon no
SureChEMBL SCHEMBL7560

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/MWUXSHHQAYIFBG-UHFFFAOYSA-N spacer
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