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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1200688
CHEMBL1200688
Compound Name ERYTHROMYCIN ETHYLSUCCINATE
ChEMBL Synonyms PEDIAMYCIN | E-MYCIN | ERYTHROPED | E.E.S. 200 | ARPIMYCIN | ERYTHROPED FTE SF | ERYMIN | E.E.S. | ROMMIX 125 | PRIMACINE | ERYTHROMYCIN ETHYL SUCCINATE | E-MYCIN E | PEDIAMYCIN 400 | ERYTHROPED SF | ERYTHROPED PI | ERYTHRODEN | ERYPED | ERYTHROPED A | WYAMYCIN | E.E.S. 400 | WYAMYCIN E | ERYTHROPED FTE | ERYTHROMYCIN ETHYLSUCCINATE | ERYTHROPED PI SF
Max Phase 4 (Approved)
Trade Names ERYTHROPED A | E.E.S. 400 | WYAMYCIN | E-MYCIN | ERYTHROMYCIN ETHYLSUCCINATE | ERYTHROPED FTE | WYAMYCIN E | E-MYCIN E | PRIMACINE | ROMMIX 125 | ERYPED | ERYTHRODEN | ERYTHROPED PI | ERYTHROPED SF | PEDIAMYCIN 400 | E.E.S. 200 | ERYTHROPED | ERYTHROPED PI SF | PEDIAMYCIN | ARPIMYCIN | E.E.S. | ERYMIN | ERYTHROPED FTE SF
Molecular Formula C43H75NO16

Additional synonyms for CHEMBL1200688 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CCOC(=O)CCC(=O)O[C@H]1[C@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[ ...
Download SMILES
Standard InChI InChI=1S/C43H75NO16/c1-15-29-43(11,52)36(48)24(5)33(47)22(3) ...
Download InChI
Standard InChI Key NSYZCCDSJNWWJL-YXOIYICCSA-N

Sources

  • British National Formulary
  • Gene Expression Atlas Compounds
  • Open TG-GATEs
  • Orange Book
  • PubChem BioAssays
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL1200688

Molecule Features

CHEMBL1200688 compound icon
Drug Type:Natural Product-derived Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Bacterial 70S ribosome inhibitor Bacterial 70S ribosome DailyMed PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
OsteomyelitisD010019EFO:0003102osteomyelitis0ClinicalTrials
Diabetes Mellitus, Type 1D003922EFO:0001359type I diabetes mellitus1ClinicalTrials
InfertilityD007246EFO:0000545infertility1ClinicalTrials

Clinical Data

ClinicalTrials.gov ERYTHROMYCIN ETHYLSUCCINATE
The Cochrane Collaboration ERYTHROMYCIN ETHYLSUCCINATE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
862.1 861.5086 2.68 12 226.28 NEUTRAL


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
17 4 2 17 4 2


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
13.09 7.59 2.72 2.31 0 60 0.16

Structural Alerts

There are 6 structural alerts for CHEMBL1200688. To view alerts please click here.

Compound Cross References

ChemSpider ChemSpider:NSYZCCDSJNWWJL-YXOIYICCSA-N
DailyMed erythromycin ethylsuccinate
PubChem SID: 144207046 SID: 46500619 SID: 49648467 SID: 855551

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1200688



ACToR 54597-56-7 41342-53-4 1264-62-6
Atlas erythromycin ethylsuccinate
BindingDB 96262
ChEBI 31555
ChemicalBook CB1701234
DrugCentral 1051
EPA CompTox Dashboard DTXSID4022993
FDA SRS 1014KSJ86F
KEGG Ligand C12796
LINCS LSM-3144
LipidMaps LMPK05000001
Mcule MCULE-3725545409
MolPort MolPort-003-666-180
Nikkaji J217.089B
PubChem 443953
Selleck erythromycin-ethylsuccinate
SureChEMBL SCHEMBL18259
ZINC ZINC000169356230

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/NSYZCCDSJNWWJL-YXOIYICCSA-N spacer
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