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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1095282
CHEMBL1095282
Compound Name CAMAZEPAM
ChEMBL Synonyms CAMAZEPAM
Max Phase 0
Trade Names
Molecular Formula C19H18ClN3O3

Additional synonyms for CHEMBL1095282 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CN(C)C(=O)OC1N=C(c2ccccc2)c3cc(Cl)ccc3N(C)C1=O
Standard InChI InChI=1S/C19H18ClN3O3/c1-22(2)19(25)26-17-18(24)23(3)15-10-9 ...
Download InChI
Standard InChI Key PXBVEXGRHZFEOF-UHFFFAOYSA-N

Sources

  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Alternate Forms of Compound in ChEMBL


CHEMBL1095282

Molecule Features

CHEMBL1095282 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Racemic Mixture Prodrug:N Oral:Unclassified Parenteral:Unclassified Topical:Unclassified Black Box:Unclassified Availability Type:Unclassified

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
ANXIETYD001007EFO:0005230ANXIETY4ATC

Clinical Data

ClinicalTrials.gov CAMAZEPAM
The Cochrane Collaboration CAMAZEPAM

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Target Predictions

The two tables below display ChEMBL single-protein targets which are predicted to interact with CHEMBL1095282. A 1uM and 10 uM cut-off have been applied to ChEMBL bioactivity data used to generate the respective models and the yellow coloured rows correspond to genuine predictions, i.e. targets not included in the original training set for this compound.


1uM


ChEMBL_ID Target Name Organism Score
CHEMBL2871 Cholecystokinin A receptor Rattus norvegicus 1.000
CHEMBL298 Cholecystokinin B receptor Homo sapiens 1.000
CHEMBL4552 Peripheral-type benzodiazepine receptor Rattus norvegicus 0.995
CHEMBL1163125 Bromodomain-containing protein 4 Homo sapiens 0.983
CHEMBL1962 GABA receptor alpha-1 subunit Homo sapiens 0.956
CHEMBL1901 Cholecystokinin A receptor Homo sapiens 0.280



10uM


ChEMBL_ID Target Name Organism Score
CHEMBL298 Cholecystokinin B receptor Homo sapiens 1.000
CHEMBL2871 Cholecystokinin A receptor Rattus norvegicus 1.000
CHEMBL4552 Peripheral-type benzodiazepine receptor Rattus norvegicus 0.995
CHEMBL1962 GABA receptor alpha-1 subunit Homo sapiens 0.963

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
371.8 371.1037 3.63 3 62.21 NEUTRAL


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
4 0 0 6 0 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- 2.21 3.11 3.11 2 26 0.83

Structural Alerts

There are 1 structural alerts for CHEMBL1095282. To view alerts please click here.

Compound Cross References

ATC N - NERVOUS SYSTEM
N05 - PSYCHOLEPTICS
N05B - ANXIOLYTICS
N05BA - Benzodiazepine derivatives
N05BA15 - camazepam

ChemSpider ChemSpider:PXBVEXGRHZFEOF-UHFFFAOYSA-N
Wikipedia Camazepam

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1095282



ACToR 36104-80-0
ChEBI 135570
DrugBank DB01489
DrugCentral 469
IBM Patent System 7518A94CB0DC4D6C4E8842FDC2151043
Nikkaji J19.779C
PubChem 37367
PubChem: Drugs of the Future 12013410
PubChem: Thomson Pharma 14978949
SureChEMBL SCHEMBL156795

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/PXBVEXGRHZFEOF-UHFFFAOYSA-N spacer
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