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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL413376
CHEMBL413376
Compound Name SURAMIN HEXASODIUM
ChEMBL Synonyms NAPHURIDE | SURAMIN SODIUM | CI-1003 | SURAMIN HEXASODIUM
Max Phase 3
Trade Names
Molecular Formula C51H34N6Na6O23S6

Additional synonyms for CHEMBL413376 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].Cc1ccc(cc1NC(=O)c2cccc(N ...
Download SMILES
Standard InChI InChI=1S/C51H40N6O23S6.6Na/c1-25-9-11-29(49(60)54-37-13-15-4 ...
Download InChI
Standard InChI Key VAPNKLKDKUDFHK-UHFFFAOYSA-H

Sources

  • PubChem BioAssays
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Alternate Forms of Compound in ChEMBL


CHEMBL413376

Molecule Features

CHEMBL413376 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:N First In Class:N Chirality:Achiral Molecule Prodrug:N Oral:Unclassified Parenteral:Unclassified Topical:Unclassified Black Box:Unclassified Availability Type:Unknown

Mechanism of Action

Mechanism of Action ChEMBL Target References
Acidic fibroblast growth factor inhibitor Acidic fibroblast growth factor PubChem PubMed PubMed PubMed PubMed PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Multiple MyelomaD009101EFO:0001378multiple myeloma2ClinicalTrials
LeishmaniasisD007896EFO:0005044Leishmaniasis3ATC
Adrenocortical CarcinomaD018268EFO:0003093adrenocortical carcinoma2ClinicalTrials
Carcinoma, Renal CellD002292EFO:0000681renal cell carcinoma1ClinicalTrials
Prostatic NeoplasmsD011471EFO:0001663prostate carcinoma3ClinicalTrials
Prostatic NeoplasmsD011471EFO:0000673prostate adenocarcinoma3ClinicalTrials
Child Development Disorders, PervasiveD002659EFO:0003756autism spectrum disorder1ClinicalTrials
TrypanosomiasisD014352DOID:10113trypanosomiasis3ATC
Breast NeoplasmsD001943EFO:0000305breast carcinoma1ClinicalTrials
Carcinoma, Non-Small-Cell LungD002289EFO:0003060non-small cell lung carcinoma2ClinicalTrials
GliomaD005910EFO:0000326central nervous system cancer2ClinicalTrials
Urinary Bladder NeoplasmsD001749EFO:0000292bladder carcinoma1ClinicalTrials

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
1297.3 1296.0469 - - - -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
- - - - - -


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - - - - - -0

Structural Alerts

There are no structural alerts for CHEMBL413376

Compound Cross References

ATC P - ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
P01 - ANTIPROTOZOALS
P01C - AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS
P01CX - Other agents against leishmaniasis and trypanosomiasis
P01CX02 - suramin sodium

ChemSpider ChemSpider:VAPNKLKDKUDFHK-UHFFFAOYSA-H
PubChem SID: 11112082 SID: 124881892 SID: 26747683 SID: 26753666 SID: 85231329

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL413376



ChEBI 9364
eMolecules 531755
EPA CompTox Dashboard DTXSID30156024
FDA SRS 89521262IH
MolPort MolPort-003-665-583
Nikkaji J166.125F
PubChem 101303499 5360 8514
PubChem: Drugs of the Future 12013770
PubChem: Thomson Pharma 14866441
SureChEMBL SCHEMBL414636

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/VAPNKLKDKUDFHK-UHFFFAOYSA-H spacer
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