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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL408403
CHEMBL408403
Compound Name ANGIOTENSIN II
ChEMBL Synonyms ANGIOTENSIN II ACETATE | ANGIOTENSIN II | Giapreza
Max Phase 4 (Approved)
Trade Names Giapreza
Molecular Formula C50H71N13O12

Additional synonyms for CHEMBL408403 found using NCI Chemical Identifier Resolver

Sources

  • DrugMatrix
  • Gene Expression Atlas Compounds
  • Manually Added Drugs
  • PubChem BioAssays
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Molecule Features

CHEMBL408403 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Type-1 angiotensin II receptor agonist Type-1 angiotensin II receptor FDA

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Shock, SepticD012772EFO:0006834septic shock4ClinicalTrials
FDA
HypertensionD006973EFO:0000537hypertension3ClinicalTrials

Clinical Data

ClinicalTrials.gov ANGIOTENSIN II
The Cochrane Collaboration ANGIOTENSIN II

HELM Notation

CHEMBL408403 HELM Notation
PEPTIDE1{D.R.V.Y.I.H.P.F}$$$$

The ChEMBL HELM monomer library is available to download here.

For more details about HELM Notation, please visit the HELM Homepage.

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Compound Cross References

ChemSpider ChemSpider:CZGUSIXMZVURDU-JZXHSEFVSA-N
DailyMed angiotensin ii acetate
PubChem SID: 50112427

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL408403



ACToR 11128-99-7
BindingDB 50236697
Brenda 661 47069 21133 141989 30756
ChEBI 58506 2719 131170
ChemicalBook CB0338057
DrugBank DB11842
DrugCentral 5272
eMolecules 29370059
EPA CompTox Dashboard DTXSID30196288
Guide to Pharmacology 2504
Human Metabolome Database HMDB0001035
KEGG Ligand C02135
LINCS LSM-42772
Metabolights MTBLC2719 MTBLC58506
MolPort MolPort-023-276-011 MolPort-042-652-607
Nikkaji J38.547F
PubChem 172198 45266664
PubChem: Thomson Pharma 14816795 14914641 16177615
Rhea 58506
SureChEMBL SCHEMBL1189 SCHEMBL20502357
ZINC ZINC000169676920

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/CZGUSIXMZVURDU-JZXHSEFVSA-N spacer
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