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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL373742
CHEMBL373742
Compound Name VASOPRESSIN
ChEMBL Synonyms VASOSTRICT | Vasophysin | Arginine Vasopressin | Leiormone | Beta-Hypophamine | PITRESSIN | VASOPRESSIN | VASOPRESSIN INJECTION
Max Phase 4 (Approved)
Trade Names Leiormone | PITRESSIN | Vasophysin | VASOSTRICT | Beta-Hypophamine
Molecular Formula C46H65N15O12S2

Additional synonyms for CHEMBL373742 found using NCI Chemical Identifier Resolver

Sources

  • Orange Book
  • PubChem BioAssays
  • Scientific Literature
  • TP-search Transporter Database
  • USP Dictionary of USAN and International Drug Names

Molecule Features

CHEMBL373742 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Vasopressin receptor agonist Vasopressin receptor IUPHAR

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Child Development Disorders, PervasiveD002659EFO:0003756autism spectrum disorder2ClinicalTrials
Hypertension, PulmonaryD006976EFO:0001361pulmonary hypertension2ClinicalTrials
Diabetes InsipidusD0039194DailyMed
DailyMed
DailyMed
DailyMed
DailyMed
DailyMed
SepsisD018805HP:0100806sepsis4DailyMed
Autistic DisorderD001321EFO:0003758autism2ClinicalTrials
Death, Sudden, CardiacD016757EFO:0004278sudden cardiac arrest3ClinicalTrials
Pleural EffusionD0109962ClinicalTrials
PainD010146EFO:0003843pain1ClinicalTrials
Shock, SepticD012772EFO:0006834septic shock3ClinicalTrials
Depressive DisorderD003866EFO:0003761unipolar depression2ClinicalTrials
Wounds and InjuriesD014947EFO:0000546injury2ClinicalTrials
Acute Lung InjuryD055371EFO:0004610acute lung injury2ClinicalTrials
Hernias, Diaphragmatic, CongenitalD065630EFO:0005207congenital heart disease2ClinicalTrials

Clinical Data

ClinicalTrials.gov VASOPRESSIN
The Cochrane Collaboration VASOPRESSIN

HELM Notation

CHEMBL373742 HELM Notation
PEPTIDE1{C.Y.F.Q.N.C.P.R.G.[am]}$PEPTIDE1,PEPTIDE1,6:R3-1:R3$$$

The ChEMBL HELM monomer library is available to download here.

For more details about HELM Notation, please visit the HELM Homepage.

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Compound Cross References

ChemSpider ChemSpider:KBZOIRJILGZLEJ-LGYYRGKSSA-N
DailyMed vasopressin
PubChem SID: 144206588 SID: 29218064

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL373742



ACToR 113-79-1
BindingDB 50044777 35667
Brenda 37486 152674 25213 206894
ChEBI 34543
DrugCentral 2810
eMolecules 37036363
EPA CompTox Dashboard DTXSID0048349
Guide to Pharmacology 2168
IBM Patent System 9A4C28BCAD0907AA5CF7E89BA5322C4B
MolPort MolPort-003-939-853
Nikkaji J1.025A
PubChem 644077
PubChem: Thomson Pharma 15411997
SureChEMBL SCHEMBL17874853 SCHEMBL43139

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/KBZOIRJILGZLEJ-LGYYRGKSSA-N spacer
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