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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1770
CHEMBL1770
Compound Name LEVAMISOLE HYDROCHLORIDE
ChEMBL Synonyms Levamisole HCl | R-12564 | Ergamisol
Max Phase 4 (Approved)
Trade Names Ergamisol
Molecular Formula C11H13ClN2S

Additional synonyms for CHEMBL1770 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES Cl.C1CN2C[C@@H](N=C2S1)c3ccccc3
Standard InChI InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)1 ...
Download InChI
Standard InChI Key LAZPBGZRMVRFKY-HNCPQSOCSA-N

Mechanism of Action

Mechanism of Action ChEMBL Target References
Nicotinic acetylcholine receptor alpha subunit agonist Nicotinic acetylcholine receptor alpha subunit PubMed PubMed

Molecule Features

CHEMBL1770 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:N Availability Type:Discontinued

Clinical Data

Number of clinical trials registered at clinicaltrials.gov
Number of reviews at The Cochrane Collaboration
Number of entries at British National Formulary

Structural Alerts

There are no structural alerts for CHEMBL1770

Alternate Forms of Compound in ChEMBL


CHEMBL1770

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Target Predictions

The two tables below display ChEMBL single-protein targets which are predicted to interact with CHEMBL1770. A 1uM and 10 uM cut-off have been applied to ChEMBL bioactivity data used to generate the respective models and the yellow coloured rows correspond to genuine predictions, i.e. targets not included in the original training set for this compound.


1uM


ChEMBL_ID Target Name Organism Score
CHEMBL1293237 Bloom syndrome protein Homo sapiens 0.614

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
204.3 204.0721 2.29 1 40.9 BASE


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
3 0 0 2 0 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- 10 1.84 -.06 1 14 0.7

Compound Cross References

ChemSpider ChemSpider:LAZPBGZRMVRFKY-HNCPQSOCSA-N
PubChem SID: 144204834 SID: 50106504 SID: 564189 SID: 56463293

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1770



ACToR 16595-80-5
ChEBI 6433
eMolecules 512018
FDA SRS DL9055K809
KEGG Ligand C07906
Mcule MCULE-7118728152
MolPort MolPort-003-666-467
PubChem 51358268 27944
PubChem: Drugs of the Future 12015289
PubChem: Thomson Pharma 14774048 15121920
Selleck Levamisole-Hydrochloride(Ergamisol)
SureChEMBL SCHEMBL19226

UniChem REST Service Call: https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/LAZPBGZRMVRFKY-HNCPQSOCSA-N spacer
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