ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1278146
CHEMBL1278146
Compound Name FAMITINIB
ChEMBL Synonyms SHR-1020
Max Phase 0
Trade Names
Molecular Formula C23H27FN4O2

Additional synonyms for CHEMBL1278146 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CCN(CC)CCN1CCc2[nH]c(\C=C\3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O
Standard InChI InChI=1S/C23H27FN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30 ...
Download InChI
Standard InChI Key GKEYKDOLBLYGRB-LGMDPLHJSA-N

Sources

  • Scientific Literature

Alternate Forms of Compound in ChEMBL


CHEMBL1278146

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
410.5 410.2118 3.3 6 68.44 BASE


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
3 2 0 6 2 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
11.73 9.81 1.64 -.54 2 30 0.72

Structural Alerts

There are 3 structural alerts for CHEMBL1278146. To view alerts please click here.

Compound Cross References

ChemSpider ChemSpider:GKEYKDOLBLYGRB-LGMDPLHJSA-N

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1278146



BindingDB 50331023
DrugBank DB11741
FDA SRS 768FW21J3L
Guide to Pharmacology 7886
Nikkaji J3.407.690A
PubChem 16662431
PubChem: Thomson Pharma 26522442
SureChEMBL SCHEMBL137251

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/GKEYKDOLBLYGRB-LGMDPLHJSA-N spacer
spacer