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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1201764
CHEMBL1201764
Compound Name FESOTERODINE
ChEMBL Synonyms FESOTERODINE | SPM 907 | Toviaz | FESOTERODINE FUMARATE | SPM 8272
Max Phase 4 (Approved)
Trade Names Toviaz
Molecular Formula C26H37NO3

Additional synonyms for CHEMBL1201764 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CC(C)N(CC[C@H](c1ccccc1)c2cc(CO)ccc2OC(=O)C(C)C)C(C)C
Standard InChI InChI=1S/C26H37NO3/c1-18(2)26(29)30-25-13-12-21(17-28)16-24( ...
Download InChI
Standard InChI Key DCCSDBARQIPTGU-HSZRJFAPSA-N

Alternate Forms of Compound in ChEMBL


CHEMBL1201764

Molecule Features

CHEMBL1201764 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Muscarinic acetylcholine receptor M2 antagonist Muscarinic acetylcholine receptor M2 DailyMed ISBN PubMed PubMed
Muscarinic acetylcholine receptor M3 antagonist Muscarinic acetylcholine receptor M3 DailyMed ISBN PubMed PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication
NOCTURIAD053158HP:0000017NOCTURIA2
POLYURIAD011141HP:0000103POLYURIA4
PROSTATIC NEOPLASMSD011471EFO:0000673PROSTATE ADENOCARCINOMA4
URINARY BLADDER, NEUROGENICD001750HP:0000011NEUROGENIC BLADDER3
URINARY INCONTINENCED014549HP:0000020URINARY INCONTINENCE4

Clinical Data

Number of clinical trials registered at clinicaltrials.gov
Number of reviews at The Cochrane Collaboration
Number of entries at British National Formulary

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
411.6 411.2773 5.71 11 49.77 BASE


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
4 1 1 4 1 1


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- 8.84 4.73 3.29 2 30 0.38

Structural Alerts

There are 3 structural alerts for CHEMBL1201764. To view alerts please click here.

Compound Cross References

ATC G - GENITO URINARY SYSTEM AND SEX HORMONES
G04 - UROLOGICALS
G04B - Urologicals
G04BD - Drugs for urinary frequency and incontinence
G04BD11 - fesoterodine

ChemSpider ChemSpider:DCCSDBARQIPTGU-HSZRJFAPSA-N
DailyMed fesoterodine fumarate
Wikipedia Fesoterodine

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1201764



ACToR 286930-02-7
ChEBI 135920
DrugBank DB06702
DrugCentral 4191
EPA CompTox Dashboard DTXSID80182853
FDA SRS 621G617227
Guide to Pharmacology 7473
Human Metabolome Database HMDB15648
IBM Patent System 3A12A4D70ED055A305E3061BF9B01899
Nikkaji J2.587.519B
PubChem 6918558
PubChem: Thomson Pharma 14781939
SureChEMBL SCHEMBL121127

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/DCCSDBARQIPTGU-HSZRJFAPSA-N spacer
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