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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL6069
Target Type SINGLE PROTEIN
Preferred Name Pantothenate synthetase
Synonyms Pantoate--beta-alanine ligase | Pantoate-activating enzyme | Pantothenate synthetase | panC
Organism Mycobacterium tuberculosis
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Pantothenate synthetase SINGLE PROTEIN P9WIL5

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0000287 (magnesium ion binding)
GO:0004592 (pantoate-beta-alanine ligase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016874 (ligase activity)
GO:0030145 (manganese ion binding)
GO:0046872 (metal ion binding)
GO Biological Process GO:0009405 (pathogenesis)
GO:0015940 (pantothenate biosynthetic process)
GO:0019482 (beta-alanine metabolic process)
GO:0033317 (pantothenate biosynthetic process from valine)
GO:0040007 (growth)

Target Cross References - Protein

canSAR P0A5R0
UniProt L0TG74 O06280 P0A5R0 P9WIL5

Target Cross References - Domain

InterPro IPR003721 (Pantoate_ligase.)
IPR014729 (Rossmann-like_a/b/a_fold.)
Pfam PF02569 (Pantoate_ligase)

Target Cross References - Structure

PDBe 1MOP 1N2B 1N2E 1N2G 1N2H 1N2I 1N2J 1N2O 2A7X 2A84 2A86 2A88 3COV 3COW 3COY 3COZ 3IMC 3IME 3IMG 3IOB 3IOC 3IOD 3IOE 3ISJ More...
CREDO 1MOP 1N2B 1N2E 1N2G 1N2H 1N2I 1N2J 1N2O 2A7X 2A84 2A86 2A88 3COV 3COW 3COY 3COZ 3IMC 3IME 3IMG 3IOB 3IOC 3IOD 3IOE 3ISJ More...
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