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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5857
Target Type SINGLE PROTEIN
Preferred Name Trace amine-associated receptor 1
Synonyms TA1 | TAAR1 | TAR1 | TRAR1 | TaR-1 | Trace amine receptor 1 | Trace amine-associated receptor 1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > trace amine receptor

Target Components

Component Description Relationship Accession
Trace amine-associated receptor 1 SINGLE PROTEIN Q96RJ0

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000146399
Ensembl ENSG00000146399
GO Cellular Component GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0001594 (trace-amine receptor activity)
GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0008227 (G-protein coupled amine receptor activity)
GO Biological Process GO:0006171 (cAMP biosynthetic process)
GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
Wikipedia TAAR1

Target Cross References - Protein

canSAR Q96RJ0
Human Protein Atlas ENSG00000146399
Guide to Pharmacology 364
Open Targets ENSG00000146399
PharmGKB PA134921784
Pharos Q96RJ0 (Tclin)
Reactome R-HSA-375280 (Amine ligand-binding receptors.)
R-HSA-418555 (G alpha (s) signalling events.)
UniProt Q2M1W5 Q3MIH8 Q5VUQ1 Q96RJ0

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR009132 (TAAR_fam.)
IPR009133 (TAAR1.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
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