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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5786
Target Type SINGLE PROTEIN
Preferred Name Leukotriene A-4 hydrolase
Synonyms LTA-4 hydrolase | LTA4H | Leukotriene A(4) hydrolase | Leukotriene A-4 hydrolase
Organism Cavia porcellus
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mae clan > metallo protease m1 family

Target Components

Component Description Relationship Accession
Leukotriene A-4 hydrolase SINGLE PROTEIN P19602

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0004177 (aminopeptidase activity)
GO:0004301 (epoxide hydrolase activity)
GO:0004463 (leukotriene-A4 hydrolase activity)
GO:0008233 (peptidase activity)
GO:0008237 (metallopeptidase activity)
GO:0008270 (zinc ion binding)
GO:0016787 (hydrolase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006508 (proteolysis)
GO:0019370 (leukotriene biosynthetic process)
GO:0043171 (peptide catabolic process)

Target Cross References - Protein

canSAR P19602
UniProt P19602

Target Cross References - Domain

InterPro IPR001930 (Peptidase_M1.)
IPR012777 (Leukotriene_A4_hydrolase.)
IPR014782 (Peptidase_M1_N.)
IPR015211 (Peptidase_M1_C.)
IPR016024 (ARM-type_fold.)
IPR034015 (M1_LTA4H.)
Pfam PF01433 (Peptidase_M1)
PF09127 (Leuk-A4-hydro_C)
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