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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5662
Target Type SINGLE PROTEIN
Preferred Name 2,3-dihydroxybenzoate-AMP ligase
Synonyms Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | mbtA
Organism Mycobacterium tuberculosis
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase SINGLE PROTEIN P71716

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Molecular Function GO:0003824 (catalytic activity)
GO:0008668 ((2,3-dihydroxybenzoyl)adenylate synthase activity)
GO:0016874 (ligase activity)
GO:0016881 (acid-amino acid ligase activity)
GO Biological Process GO:0008152 (metabolic process)
GO:0010106 (cellular response to iron ion starvation)
GO:0019540 (siderophore biosynthetic process from catechol)

Target Cross References - Protein

canSAR P71716
UniProt F2GI64 I6Y957 P71716 Q7D787

Target Cross References - Domain

InterPro IPR000873 (AMP-dep_Synth/Lig.)
IPR025110 (AMP-bd_C.)
Pfam PF00501 (AMP-binding)
PF13193 (AMP-binding_C)
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