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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5567
Target Type SINGLE PROTEIN
Preferred Name Luciferin 4-monooxygenase
Synonyms Luciferase | Luciferin 4-monooxygenase
Organism Photinus pyralis
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Luciferin 4-monooxygenase SINGLE PROTEIN P08659

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005777 (peroxisome)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0003824 (catalytic activity)
GO:0004497 (monooxygenase activity)
GO:0005524 (ATP binding)
GO:0016491 (oxidoreductase activity)
GO:0046872 (metal ion binding)
GO:0047077 (Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity)
GO:0051087 (chaperone binding)
GO Biological Process GO:0008152 (metabolic process)
GO:0008218 (bioluminescence)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

canSAR P08659
IntAct P08659
UniProt P08659 Q27755

Target Cross References - Domain

InterPro IPR000873 (AMP-dep_Synth/Lig.)
IPR020845 (AMP-binding_CS.)
IPR025110 (AMP-bd_C.)
IPR027380 (Luciferase_N_dom_sf.)
Pfam PF00501 (AMP-binding)
PF13193 (AMP-binding_C)

Target Cross References - Structure

PDBe 1BA3 1LCI 3IEP 3IER 3IES 3RIX 4E5D 4G36 4G37 5DV9 5DWV 5GYZ 5GZ2 5KYT 5KYV 5WYS
CREDO 1BA3 1LCI 3IEP 3IER 3IES 3RIX 4E5D 4G36 4G37 5DV9 5DWV 5GYZ 5GZ2 5KYT 5KYV 5WYS
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