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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5471
Target Type SINGLE PROTEIN
Preferred Name Beta-1 adrenergic receptor
Synonyms ADRB1 | Beta-1 adrenergic receptor
Organism Cavia porcellus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > adrenergic receptor

Target Components

Component Description Relationship Accession
Beta-1 adrenergic receptor SINGLE PROTEIN B0FL73

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005622 (intracellular)
GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004935 (adrenergic receptor activity)
GO:0004940 (beta1-adrenergic receptor activity)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007189 (adenylate cyclase-activating G-protein coupled receptor signaling pathway)
GO:0045823 (positive regulation of heart contraction)
GO:0071875 (adrenergic receptor signaling pathway)

Target Cross References - Protein

canSAR B0FL73
UniProt B0FL73

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR000507 (ADRB1_rcpt.)
IPR002233 (ADR_fam.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
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