ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL4909
Target Type SINGLE PROTEIN
Preferred Name Prostanoid EP2 receptor
Synonyms PGE receptor EP2 subtype | PGE2 receptor EP2 subtype | Prostaglandin E2 receptor EP2 subtype | Prostanoid EP2 receptor | Ptger2
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > lipid-like ligand receptor (family a gpcr) > prostanoid receptor

Target Components

Component Description Relationship Accession
Prostaglandin E2 receptor EP2 subtype SINGLE PROTEIN Q62928

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005622 (intracellular)
GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004957 (prostaglandin E receptor activity)
GO Biological Process GO:0001501 (skeletal system development)
GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007189 (adenylate cyclase-activating G-protein coupled receptor signaling pathway)
GO:0032496 (response to lipopolysaccharide)
GO:0032570 (response to progesterone)
GO:0042127 (regulation of cell proliferation)
GO:0071380 (cellular response to prostaglandin E stimulus)

Target Cross References - Protein

canSAR Q62928
Guide to Pharmacology 341
Reactome R-RNO-391908 (Prostanoid ligand receptors.)
R-RNO-418555 (G alpha (s) signalling events.)
UniProt Q547S0 Q62928

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR001923 (Prostglndn_EP2_rcpt.)
IPR008365 (Prostanoid_rcpt.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
spacer
spacer