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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4796
Target Type SINGLE PROTEIN
Preferred Name Beta-chymotrypsin
Synonyms CTRB1 | Chymotrypsin B chain A | Chymotrypsin B chain B | Chymotrypsin B chain C | Chymotrypsinogen B | Synonyms=CTRB
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > serine protease > serine protease pa clan > serine protease s1a subfamily

Target Components

Component Description Relationship Accession
Chymotrypsinogen B SINGLE PROTEIN P17538

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000168925
Ensembl ENSG00000168925
GO Cellular Component GO:0005576 (extracellular region)
GO:0005615 (extracellular space)
GO Molecular Function GO:0004252 (serine-type endopeptidase activity)
GO:0008233 (peptidase activity)
GO:0008236 (serine-type peptidase activity)
GO:0016787 (hydrolase activity)
GO Biological Process GO:0006508 (proteolysis)
GO:0007586 (digestion)
GO:0009235 (cobalamin metabolic process)
GO:0022617 (extracellular matrix disassembly)

Target Cross References - Protein

canSAR P17538
Human Protein Atlas ENSG00000168925
Open Targets ENSG00000168925
Reactome R-HSA-1592389 (Activation of Matrix Metalloproteinases.)
R-HSA-196741 (Cobalamin (Cbl, vitamin B12) transport and metabolism.)
UniProt P17538

Target Cross References - Domain

InterPro IPR001254 (Trypsin_dom.)
IPR001314 (Peptidase_S1A.)
IPR009003 (Peptidase_S1_PA.)
IPR018114 (TRYPSIN_HIS.)
IPR033116 (TRYPSIN_SER.)
Pfam PF00089 (Trypsin)
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