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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4779
Target Type SINGLE PROTEIN
Preferred Name Papain
Synonyms Allergen=Car p 1 | PPI | Papain | Papaya proteinase I
Organism Carica papaya
Species Group No
Protein Target Classification
  • enzyme > protease > cysteine protease > cysteine protease ca clan > cysteine protease c1a family

Target Components

Component Description Relationship Accession
Papain SINGLE PROTEIN P00784

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Molecular Function GO:0008233 (peptidase activity)
GO:0008234 (cysteine-type peptidase activity)
GO:0016787 (hydrolase activity)
GO:0097655 (serpin family protein binding)
GO Biological Process GO:0006508 (proteolysis)

Target Cross References - Protein

canSAR P00784
UniProt P00784

Target Cross References - Domain

InterPro IPR000169 (Pept_cys_AS.)
IPR000668 (Peptidase_C1A_C.)
IPR013128 (Peptidase_C1A.)
IPR013201 (Prot_inhib_I29.)
IPR025660 (Pept_his_AS.)
IPR025661 (Pept_asp_AS.)
Pfam PF00112 (Peptidase_C1)
PF08246 (Inhibitor_I29)

Target Cross References - Structure

PDBe 1BP4 1BQI 1CVZ 1KHP 1KHQ 1PAD 1PE6 1PIP 1POP 1PPD 1PPN 1PPP 1STF 2CIO 2PAD 3E1Z 3IMA 3LFY 3TNX 3USV 4KP9 4PAD 4QRG 4QRV More...
CREDO 1BP4 1BQI 1CVZ 1KHP 1KHQ 1PAD 1PE6 1PIP 1POP 1PPD 1PPN 1PPP 1STF 2CIO 2PAD 3E1Z 3IMA 3LFY 3TNX 3USV 4KP9 4PAD 4QRG 4QRV More...
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