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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4153
Target Type SINGLE PROTEIN
Preferred Name Sigma-1 receptor
Synonyms OPRS1 | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Organism Cavia porcellus
Species Group No
Protein Target Classification
  • other membrane protein

Target Components

Component Description Relationship Accession
Sigma non-opioid intracellular receptor 1 SINGLE PROTEIN Q60492

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005634 (nucleus)
GO:0005635 (nuclear envelope)
GO:0005637 (nuclear inner membrane)
GO:0005640 (nuclear outer membrane)
GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0005811 (lipid particle)
GO:0005886 (plasma membrane)
GO:0014069 (postsynaptic density)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0030054 (cell junction)
GO:0030426 (growth cone)
GO:0031410 (cytoplasmic vesicle)
GO:0042995 (cell projection)
GO:0045202 (synapse)
GO:0045211 (postsynaptic membrane)
GO Biological Process GO:0006869 (lipid transport)
GO:0043523 (regulation of neuron apoptotic process)

Target Cross References - Protein

canSAR Q60492
UniProt Q60492

Target Cross References - Domain

InterPro IPR006716 (ERG2_sigma1_rcpt-like.)
Pfam PF04622 (ERG2_Sigma1R)
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