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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3952
Preferred Name Kappa opioid receptor
Synonyms K-OR-1 | KOR-1 | Kappa-type opioid receptor | OPRK1
Organism Cavia porcellus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > peptide receptor (family a gpcr) > short peptide receptor (family a gpcr) > opioid receptor

Target Components

Component Description Relationship Accession
Kappa-type opioid receptor SINGLE PROTEIN P41144

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3038518 mu/kappa opioid receptor PROTEIN FAMILY
CHEMBL2111465 Opioid receptor (mu and kappa) SELECTIVITY GROUP

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004985 (opioid receptor activity)
GO:0038048 (dynorphin receptor activity)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007200 (phospholipase C-activating G-protein coupled receptor signaling pathway)
GO:0007610 (behavior)
GO:0007626 (locomotory behavior)
GO:0019233 (sensory perception of pain)
GO:0031635 (adenylate cyclase-inhibiting opioid receptor signaling pathway)
GO:0046877 (regulation of saliva secretion)

Target Cross References - Protein

canSAR P41144
UniProt P41144

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR000452 (Kappa_opi_rcpt.)
IPR001418 (Opioid_rcpt.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)