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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3912
Target Type SINGLE PROTEIN
Preferred Name Carbonic anhydrase XIII
Synonyms CA-XIII | CA13 | Carbonate dehydratase XIII | Carbonic anhydrase 13 | Carbonic anhydrase XIII
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > lyase

Target Components

Component Description Relationship Accession
Carbonic anhydrase 13 SINGLE PROTEIN Q8N1Q1

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2095180 Carbonic anhydrase PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000185015
Ensembl ENSG00000185015
GO Cellular Component GO:0005829 (cytosol)
GO:0043209 (myelin sheath)
GO:0043231 (intracellular membrane-bounded organelle)
GO Molecular Function GO:0004089 (carbonate dehydratase activity)
GO:0008270 (zinc ion binding)
GO:0016829 (lyase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006730 (one-carbon metabolic process)
GO:0015701 (bicarbonate transport)

Target Cross References - Protein

canSAR Q8N1Q1
Human Protein Atlas ENSG00000185015
IntAct Q8N1Q1
Open Targets ENSG00000185015
PharmGKB PA134891311
Reactome R-HSA-1475029 (Reversible hydration of carbon dioxide.)
UniProt Q8N1Q1

Target Cross References - Domain

InterPro IPR001148 (Carbonic_anhydrase_a.)
IPR018338 (Carbonic_anhydrase_a-class_CS.)
IPR023561 (Carbonic_anhydrase_a-class.)
IPR036398 (Carbonic_anhydrase_a_sf.)
Pfam PF00194 (Carb_anhydrase)

Target Cross References - Structure

PDBe 3CZV 3D0N 3DA2 4HU1 4KNM 4KNN 4QIZ 4QJP 4QJX 4QSJ 5E2N 5LLA 5LLN
CREDO 3CZV 3D0N 3DA2 4HU1 4KNM 4KNN 4QIZ 4QJP 4QJX 4QSJ 5E2N 5LLA 5LLN
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